SCHEMBL1129170

SCHEMBL1129170

CC(=O)NOc1ccccc1C(=O)O.c1cc2ccc1o2

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.51
HSD17B10 Q99714 6/20 0.51
HPGD P15428 6/20 0.51
ALDH1A1 P00352 7/20 0.50
ESR1 P03372 1/20 0.50
ITGB3 P05106 1/20 0.50
ITGA2B P08514 1/20 0.50
HMGB1 P09429 1/20 0.50
TSHR P16473 1/20 0.50
GGT1 P19440 1/20 0.50
PTGS1 P23219 1/20 0.50
PTGS2 P35354 1/20 0.50
BLM P54132 1/20 0.50
NAPRT Q6XQN6 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
LMNA P02545 1/20 0.45
CYP1A2 P05177 1/20 0.45
CYP2C9 P11712 1/20 0.45
HTT P42858 2/20 0.44
USP2 O75604 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38660686 0.91 KDM4E (0.61) KDM4EHSD17B10HPGDALDH1A1ESR1
SCHEMBL1966422 0.91 KDM4E (0.61) KDM4EHSD17B10HPGDALDH1A1ESR1
SCHEMBL27762366 0.89 KDM4E (0.59) KDM4EHSD17B10HPGDALDH1A1ESR1
SCHEMBL27784009 0.89 KDM4E (0.59) KDM4EHSD17B10HPGDALDH1A1ESR1
SCHEMBL1130035 0.86 KDM4E (0.56) KDM4EHSD17B10HPGDALDH1A1ESR1
SCHEMBL1129695 0.82 KDM4E (0.51) KDM4EHSD17B10HPGDALDH1A1ESR1
SCHEMBL27762367 0.76 SLC6A3 (0.56) KDM4EHSD17B10HPGDALDH1A1TSHR
SCHEMBL1982429 0.75 KDM4E (0.53) KDM4EHSD17B10HPGDALDH1A1ESR1
SCHEMBL3485366 0.75 KDM4E (0.53) KDM4EHSD17B10HPGDALDH1A1ESR1
SCHEMBL11127664 0.75 KDM4E (0.53) KDM4EHSD17B10HPGDALDH1A1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8283287-B2 Thermosensitive recording material RICOH COMPANY, LTD. (JP) 2012-10-09 US disclosed
EP-2036737-B1 Thermosensitive recording material RICOH CO LTD (JP) 2011-02-16 EP disclosed
US-20090075817-A1 THERMOSENSITIVE RECORDING MATERIAL RICOH COMPANY, LTD. (JP) 2009-03-19 US disclosed
EP-2036737-A1 Thermosensitive recording material Ricoh Company, Ltd. (JP) 2009-03-18 EP disclosed
US-4918047-A CONTAINING OXYSALICYLIC ACID DERIVATIVE AND ZINC COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1990-04-17 US disclosed
EP-0253666-A2 Heat-sensitive recording material containing dye-forming components FUJI PHOTO FILM CO., LTD. (JP) 1988-01-20 EP disclosed