SCHEMBL11292063

SCHEMBL11292063

O=S(=O)(O)c1cc(Br)cc(C(F)(F)F)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACP1 P24666 2/20 0.49
NOTUM Q6P988 1/20 0.49
CNR1 P21554 3/20 0.47
CES2 O00748 1/20 0.41
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
MMP1 P03956 1/20 0.39
MMP2 P08253 1/20 0.39
MMP9 P14780 1/20 0.39
MMP8 P22894 1/20 0.39
MMP13 P45452 1/20 0.39
DDR1 Q08345 1/20 0.37
TAS2R14 Q9NYV8 1/20 0.37
MAPT P10636 2/20 0.36
CA5A P35218 1/20 0.36
CA9 Q16790 1/20 0.36
LCK P06239 1/20 0.35
FYN P06241 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13277683 0.98 ACP1 (0.48) ACP1NOTUMCNR1CES2CA1
SCHEMBL109565 0.86 CES2 (0.54) ACP1CNR1CES2CA1CA2
SCHEMBL21522543 0.84 CES2 (0.52) ACP1CNR1CES2CA1CA2
SCHEMBL9617536 0.84 CES2 (0.52) ACP1CNR1CES2CA1CA2
SCHEMBL21522647 0.84 CES2 (0.52) ACP1CNR1CES2CA1CA2
SCHEMBL21522570 0.84 CES2 (0.52) ACP1CNR1CES2CA1CA2
SCHEMBL4807857 0.81 KIF11 (0.47) ACP1NOTUMCNR1CA1CA2
SCHEMBL12098234 0.81 NOTUM (0.49) ACP1NOTUMCNR1CES2CA1
SCHEMBL30253146 0.81 NOTUM (0.49) ACP1NOTUMCNR1CES2CA1
SCHEMBL700367 0.81 NOTUM (0.45) ACP1NOTUMCNR1CES2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3365168-B1 LIGHTWEIGHT FLAME RETARDANT THERMOPLASTIC STRUCTURES SCHNELLER LLC (US) 2021-06-30 EP claimed
US-4206110-A ORGANIC SULFONIC ACID SALT BAYER AKTIENGESELLSCHAFT (DE) 1980-06-03 US claimed
EP-0003990-B1 POLYARYL SULPHONES HAVING AN IMPROVED STRESS-CORROSION RESISTANCE. BAYER AG (DE) 1982-01-27 EP disclosed
US-4256862-A Polyaryl-sulphones containing an ammonium or metal salt of an organic sulphonic acid BAYER AKTIENGESELLSCHAFT (DE) 1981-03-17 US disclosed
US-4206110-A ORGANIC SULFONIC ACID SALT BAYER AKTIENGESELLSCHAFT (DE) 1980-06-03 US disclosed