Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | SI | P14410 | 2/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | PTPRB | P23467 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | MMP1 | P03956 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27600925 | 0.93 | CA1 (0.39) | SMN1; SMN2CA1CA2ALDH1A1ZDHHC7 | |
| SCHEMBL28259311 | 0.89 | CA1 (0.37) | SMN1; SMN2CA1CA2ALDH1A1ZDHHC7 | |
| Acetoacetic Acid SCHEMBL6899791 | 0.88 | MGAM (0.37) | SMN1; SMN2CA1CA2ZDHHC7MGAM | |
| SCHEMBL2097237 | 0.87 | SMN1; SMN2 (0.50) | SMN1; SMN2CA1CA2ALDH1A1ZDHHC7 | |
| SCHEMBL11347511 | 0.82 | SMN1; SMN2 (0.46) | SMN1; SMN2CA1CA2ALDH1A1ZDHHC7 | |
| SCHEMBL13751258 | 0.82 | SMN1; SMN2 (0.40) | SMN1; SMN2CA1CA2ALDH1A1ZDHHC7 | |
| SCHEMBL3883424 | 0.82 | SMN1; SMN2 (0.46) | SMN1; SMN2CA1CA2ZDHHC7MGAM | |
| SCHEMBL489101 | 0.81 | ALDH1A1 (0.33) | SMN1; SMN2CA1CA2ALDH1A1ZDHHC7 | |
| SCHEMBL4771674 | 0.81 | CA1 (0.45) | SMN1; SMN2CA1CA2ALDH1A1ZDHHC7 | |
| SCHEMBL27958359 | 0.81 | SMN1; SMN2 (0.41) | SMN1; SMN2CA1CA2ALDH1A1ZDHHC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114349635-B | Synthesis method of dolutegravir core intermediate | 瑞孚信江苏药业股份有限公司 | 2023-09-01 | — | — | CN | claimed |
| CN-111253834-B | Moisture-cured epoxy coating and preparation method thereof | 滨州学院 | 2022-05-24 | — | — | CN | claimed |
| CN-113683980-A | High-temperature-resistant adhesive tape for semiconductor packaging and preparation method thereof | 芜湖徽氏新材料科技有限公司 | 2021-11-23 | — | — | CN | claimed |
| CN-111253834-A | Moisture-curing epoxy coating and preparation method thereof | 滨州学院 | 2020-06-09 | — | — | CN | claimed |
| CN-111072552-A | Preparation method of cilnidipine | 湖南九典制药股份有限公司 | 2020-04-28 | — | — | CN | claimed |
| US-20200079965-A1 | POLYURETHANE COATING COMPOSITION | SWIMC LLC (US) | 2020-03-12 | — | — | US | claimed |
| CN-110691800-A | Polyurethane coating composition | 宣伟投资管理有限公司 | 2020-01-14 | — | — | CN | claimed |
| US-9981917-B2 | Preparation method for revaprazan hydrochloride | JIANGSU TASLY DIYI PHARMACEUTICAL CO., LTD. (CN) | 2018-05-29 | — | — | US | claimed |
| CN-115572257-B | Synthesis method of pyridone compound | 江西帝劢药业有限公司 | 2024-07-09 | — | — | CN | disclosed |
| EP-4077455-B1 | NON AQUEOUS CROSSLINKABLE COMPOSITION | ALLNEX NETHERLANDS BV (NL) | 2024-06-12 | — | — | EP | disclosed |
| CN-114846049-B | Nonaqueous crosslinkable compositions | 湛新荷兰有限公司 | 2024-05-24 | — | — | CN | disclosed |
| EP-4359482-A1 | NON AQUEOUS CROSSLINKABLE COMPOSITION | Allnex Netherlands B.V. (NL) | 2024-05-01 | — | — | EP | disclosed |
| CN-117924276-A | Preparation method of non-neridrone | 成都伊诺达博医药科技有限公司 | 2024-04-26 | — | — | CN | disclosed |
| US-11912707-B2 | Mitragynine alkaloids as opioid receptor modulators | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2024-02-27 | — | — | US | disclosed |
| US-5245056-A | PRODUCTION OF OXETANONES | HOFFMANN-LA ROCHE INC. (US) | 1993-09-14 | — | — | US | disclosed |
| US-5200518-A | Reduced side effcts | KANGWEON NATIONAL UNIVERSITY (KR) | 1993-04-06 | — | — | US | disclosed |
| EP-0114059-B1 | METHOD OF PREPARING A POLYAMIDE ACID COMPOSITION FOR PREPARING POLYIMIDE | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1989-06-14 | — | — | EP | disclosed |
| US-4515915-A | Polyamide acid composition for preparing polyimide | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1985-05-07 | — | — | US | disclosed |
| EP-0114059-A2 | Method of preparing a polyamide acid composition for preparing polyimide | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1984-07-25 | — | — | EP | disclosed |
| US-4007282-A | Lowering lipid and sugar levels in the blood with a bis(4-hydroxyphenyl)alkanoic acid or ester thereof | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11912707-B2 | Mitragynine alkaloids as opioid receptor modulators | OPRK1, OPRM1, OPRD1 | SMN1; SMN2 2791/4885CA1 4155/4885CA2 3431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.