Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.40 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8927341 | 0.78 | SMN1; SMN2 (0.43) | MEN1KMT2ALMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL5912618 | 0.78 | ALDH1A1 (0.43) | MEN1KMT2ALMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL6410482 | 0.76 | ALDH1A1 (0.46) | KMT2ANPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL29951428 | 0.75 | ALDH1A3 (0.60) | MEN1KMT2ANPC1POLBRAB9A | |
| SCHEMBL599867 | 0.75 | ALDH1A3 (0.60) | MEN1KMT2ANPC1POLBRAB9A | |
| Dioxane SCHEMBL28400958 | 0.74 | NPC1 (0.55) | NPC1POLBRAB9AL3MBTL1SRC | |
| SCHEMBL10990952 | 0.74 | NPC1 (0.50) | MEN1KMT2ANPC1POLBRAB9A | |
| SCHEMBL17420568 | 0.73 | KCNA5 (0.43) | LMNASMN1; SMN2L3MBTL1ALDH1A1TSHR | |
| SCHEMBL11683561 | 0.72 | SRC (0.53) | MEN1KMT2ANPC1POLBRAB9A | |
| SCHEMBL9059708 | 0.72 | MAOA (0.54) | MEN1KMT2ANPC1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336374-A | HYPOGLYCEMIC AGENTS | NIPPON SHINYAKU CO., LTD. (JP) | 1982-06-22 | — | — | US | disclosed |