SCHEMBL11292307

SCHEMBL11292307

COC(=O)C1(CC2CCCCC2)CC1

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.45
CYP4A11 Q02928 1/20 0.45
MAPT P10636 1/20 0.41
EPHX1 P07099 3/20 0.37
NPSR1 Q6W5P4 2/20 0.37
SLC1A3 P43003 3/20 0.37
SLC1A2 P43004 3/20 0.37
SLC1A1 P43005 3/20 0.37
ALDH1A1 P00352 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
EPHX2 P34913 2/20 0.36
HPGD P15428 1/20 0.35
KMT2A Q03164 1/20 0.35
CYP2C19 P33261 1/20 0.35
ADAM17 P78536 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10086984 0.87 CYP4F2 (0.50) CYP4F2CYP4A11MAPTNPSR1ALDH1A1
SCHEMBL13611665 0.75 MAPT (0.46) CYP4F2CYP4A11MAPTEPHX1NPSR1
SCHEMBL4132172 0.75 POLB (0.44) ALDH1A1L3MBTL1KMT2A
SCHEMBL5729124 0.75 ATM (0.37) CYP4F2CYP4A11MAPTKMT2A
SCHEMBL7421923 0.74 CYP2C19 (0.40) EPHX1SLC1A3SLC1A2SLC1A1HPGD
SCHEMBL1202865 0.73 MAPT (0.44) CYP4F2CYP4A11MAPTEPHX1NPSR1
SCHEMBL6623827 0.73 CYP4F2 (0.44) CYP4F2CYP4A11MAPTNPSR1ALDH1A1
SCHEMBL7416623 0.72 ALOX5 (0.41) EPHX1SLC1A3SLC1A2SLC1A1HPGD
SCHEMBL11346600 0.71 CYP2C19 (0.52) EPHX1SLC1A3SLC1A2SLC1A1EPHX2
SCHEMBL6586703 0.71 CYP2C19 (0.52) EPHX1SLC1A3SLC1A2SLC1A1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4358459-A Cyclopropane carboxylic acid and process for their production and use DEGUSSA AKTIENGESELLSCHAFT (DE) 1982-11-09 US disclosed