Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 4/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19530997 | 0.87 | CYP3A4 (0.43) | CYP3A4TDP1HTR2ATAAR1HRH1 | |
| SCHEMBL10298220 | 0.79 | TDP1 (0.36) | CYP3A4TDP1 | |
| SCHEMBL2359631 | 0.79 | TP53 (0.36) | CYP3A4TDP1SMN1; SMN2 | |
| SCHEMBL17190349 | 0.77 | TAAR1 (0.45) | HTR2ATAAR1SMN1; SMN2HRH1 | |
| SCHEMBL17598759 | 0.76 | TDP1 (0.43) | TDP1 | |
| SCHEMBL17190348 | 0.74 | HTR2A (0.46) | HTR2ATAAR1HRH1 | |
| SCHEMBL17190352 | 0.74 | SIGMAR1 (0.43) | CYP3A4HTR2ASMN1; SMN2HRH1ADRA2C | |
| SCHEMBL9864179 | 0.73 | CYP3A4 (0.39) | CYP3A4TDP1AOC3 | |
| SCHEMBL10314926 | 0.73 | KCNH2 (0.46) | TDP1 | |
| SCHEMBL17190351 | 0.73 | LTA4H (0.39) | CYP3A4TDP1HTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4328364-A | RHODIUM CATALYST | SNAMPROGETTI, S.P.A. (IT) | 1982-05-04 | — | — | US | disclosed |
| US-4239914-A | Process for preparing 2-(6'-methoxy-2'-naphthyl)-propionic acid | MONTEDISON S.P.A. (IT) | 1980-12-16 | — | — | US | disclosed |