Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | BAD | Q92934 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7938527 | 0.81 | MEN1 (0.59) | CES2CES1BCL2L1BADCA1 | |
| SCHEMBL23358694 | 0.77 | ESR1 (0.45) | CES2CES1BCL2L1BADMEN1 | |
| SCHEMBL23358695 | 0.77 | ESR1 (0.45) | CES2CES1BCL2L1BADMEN1 | |
| SCHEMBL27991299 | 0.75 | CES2 (0.43) | CES2CES1CA1CA2CYP3A4 | |
| SCHEMBL5391549 | 0.75 | CES2 (0.52) | CES2CES1BCL2L1BADCA1 | |
| SCHEMBL5391555 | 0.75 | CES2 (0.52) | CES2CES1BCL2L1BADCA1 | |
| SCHEMBL9495925 | 0.73 | TSHR (0.77) | CES2CES1MEN1KMT2ACYP3A4 | |
| SCHEMBL23344842 | 0.72 | BCL2L1 (0.74) | CES2CES1BCL2L1BADCA1 | |
| SCHEMBL9495547 | 0.72 | MEN1 (0.48) | CES2CES1BCL2L1BADCA1 | |
| SCHEMBL9494935 | 0.72 | MEN1 (0.48) | CES2CES1CA1CA2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0065354-A1 | Process for the preparation of 1,1-bis phenyl-2-haloalkan-1-ols | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-11-24 | — | — | EP | disclosed |