Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | BAD | Q92934 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9495925 | 0.91 | TSHR (0.77) | MEN1KMT2ACYP3A4TSHRMAPK1 | |
| SCHEMBL9495547 | 0.89 | MEN1 (0.48) | MEN1KMT2ACYP3A4TSHRMAPK1 | |
| SCHEMBL9494935 | 0.89 | MEN1 (0.48) | MEN1KMT2ACYP3A4TSHRMAPK1 | |
| SCHEMBL11293096 | 0.81 | CES2 (0.46) | MEN1KMT2ACYP3A4TSHRMAPK1 | |
| SCHEMBL5391555 | 0.77 | CES2 (0.52) | CES2CES1CA1CA2BCL2L1 | |
| SCHEMBL5391549 | 0.77 | CES2 (0.52) | CES2CES1CA1CA2BCL2L1 | |
| SCHEMBL126413 | 0.74 | MEN1 (1.00) | MEN1KMT2ACYP3A4TSHRMAPK1 | |
| Dichlorodiphenyldichloroethylene SCHEMBL177472 | 0.74 | TSHR (1.00) | MEN1KMT2ACYP3A4TSHRMAPK1 | |
| SCHEMBL23358695 | 0.74 | ESR1 (0.45) | MEN1KMT2ATSHRMAPK1CES2 | |
| SCHEMBL23358694 | 0.74 | ESR1 (0.45) | MEN1KMT2ATSHRMAPK1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242654-B1 | REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND | MITSUI CHEMICALS, INC. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-1013629-A1 | Preparation process of fluorine subsituted aromatic compound | Mitsui Chemicals, Inc. (JP) | 2000-06-28 | — | — | EP | disclosed |
| EP-0352956-B1 | PROCESS FOR THE PRODUCTION OF HALOBENZOPHENONE DERIVATIVES | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1993-03-17 | — | — | EP | disclosed |
| US-4960945-A | Process for the production of halobenzophenone derivatives | KUREHA KAGAKU KOGYO K.K. (JP) | 1990-10-02 | — | — | US | disclosed |
| EP-0352956-A1 | Process for the production of halobenzophenone derivatives | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-01-31 | — | — | EP | disclosed |
| EP-0101760-B1 | PROCESS FOR PRODUCING FLUOROBENZOPHENONE DERIVATIVES | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1986-02-12 | — | — | EP | disclosed |
| US-4453009-A | HALOGEN-FLUORINE EXCHANGE BETWEEN CORRESPONDING 4-HALOGENO- OR 4,4-DIHALOGENOBENZOPHENONE AND ALKALI FLUORIDE | MITSUI TOATSU CHEMICALS, INC. (JP) | 1984-06-05 | — | — | US | disclosed |
| EP-0101760-A1 | Process for producing fluorobenzophenone derivatives | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1984-03-07 | — | — | EP | disclosed |