SCHEMBL11293804

SCHEMBL11293804

ClC(Cl)=CCOc1cccc(Oc2ccccc2)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.48
ALDH1A1 P00352 6/20 0.48
SMN1; SMN2 Q16637 1/20 0.44
TDP1 Q9NUW8 3/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
ATM Q13315 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
HTR1D P28221 1/20 0.43
HTR1B P28222 1/20 0.43
AKR1C3 P42330 1/20 0.42
MAOB P27338 1/20 0.42
HTT P42858 3/20 0.41
LMNA P02545 2/20 0.41
MAPT P10636 1/20 0.41
MITF O75030 1/20 0.41
POLB P06746 1/20 0.41
MAPK1 P28482 1/20 0.41
TSHR P16473 2/20 0.40
LTA4H P09960 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11754392 0.88 HTT (0.51) SMN1; SMN2MAOBHTTTSHRLTA4H
SCHEMBL8520882 0.84 HTT (0.53) ALDH1A1MAOBHTTLMNA
SCHEMBL8638861 0.80 AR (0.38) KDM4EALDH1A1SMN1; SMN2MEN1KMT2A
SCHEMBL8902032 0.80 LOX (0.36) KDM4EALDH1A1SMN1; SMN2TDP1MEN1
SCHEMBL8407336 0.80 LMNA (0.39) TDP1ATML3MBTL1LMNATSHR
SCHEMBL8656061 0.79 FFAR1 (0.46) TDP1ATML3MBTL1LMNA
SCHEMBL11638164 0.78 KDM4E (0.45) KDM4EALDH1A1SMN1; SMN2TDP1MEN1
SCHEMBL12879338 0.78 ACHE (0.46) ALDH1A1SMN1; SMN2TDP1KMT2AL3MBTL1
SCHEMBL8635779 0.78 AR (0.39) ALDH1A1SMN1; SMN2MEN1KMT2AMAOB
SCHEMBL8409298 0.76 SRD5A2 (0.40) MAOBHTTLTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4334104-A Hydroquinone diether having juvenile hormone and acaricide activity MONTEDISON S.P.A. (IT) 1982-06-08 US disclosed