Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | COMT | P21964 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | IDH1 | O75874 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12441468 | 0.80 | HSD17B10 (0.47) | GLO1HSD17B10L3MBTL1HSP90AA1COMT | |
| SCHEMBL5913971 | 0.78 | L3MBTL1 (0.50) | GLO1HSD17B10L3MBTL1HSP90AA1BRD4 | |
| SCHEMBL11310589 | 0.78 | KDM4E (0.49) | GLO1L3MBTL1HSP90AA1IDH1ALDH1A1 | |
| SCHEMBL14063583 | 0.77 | COMT (0.47) | GLO1HSD17B10L3MBTL1HSP90AA1COMT | |
| SCHEMBL7359280 | 0.73 | ALDH1A1 (0.49) | GLO1HSD17B10L3MBTL1COMTIDH1 | |
| SCHEMBL10726835 | 0.71 | GLO1 (0.65) | GLO1L3MBTL1HSP90AA1IDH1 | |
| SCHEMBL11424614 | 0.71 | PTGS1 (0.44) | HSD17B10L3MBTL1COMTHDAC4HDAC2 | |
| SCHEMBL8957061 | 0.70 | IDH1 (0.37) | HSP90AA1COMTIDH1ALDH1A1KMT2A | |
| SCHEMBL10059749 | 0.69 | SMN1; SMN2 (0.60) | GLO1HSD17B10L3MBTL1HSP90AA1COMT | |
| SCHEMBL10796031 | 0.69 | CA12 (0.43) | HSD17B10ALDH1A1LMNASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0013936-B1 | REACTIVE AZO DYESTUFFS, THEIR PREPARATION AND THEIR USE IN DYEING MATERIALS CONTAINING HYDROXYL GROUPS AND AMIDE GROUPS | BAYER AG (DE) | 1982-09-22 | — | — | EP | disclosed |
| US-4299764-A | Azo reactive dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1981-11-10 | — | — | US | disclosed |
| EP-0013936-A1 | Reactive azo dyestuffs, their preparation and their use in dyeing materials containing hydroxyl groups and amide groups | BAYER AG (DE) | 1980-08-06 | — | — | EP | disclosed |
| US-4067864-A | FOR CELLULOSE OR POLYAMIDES | CIBA-GEIGY AG (CH) | 1978-01-10 | — | — | US | disclosed |