SCHEMBL11294658

SCHEMBL11294658

C/C(C=O)=C\COc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.46
TSHR P16473 1/20 0.46
BTN3A1 O00481 2/20 0.43
AOC3 Q16853 1/20 0.43
ALOX15 P16050 1/20 0.42
MTNR1A P48039 4/20 0.42
MTNR1B P49286 4/20 0.42
NDUFS8 O00217 1/20 0.42
COXFA4 O00483 1/20 0.42
NDUFAB1 O14561 1/20 0.42
NDUFA1 O15239 1/20 0.42
NDUFS4 O43181 1/20 0.42
NDUFB5 O43674 1/20 0.42
NDUFB3 O43676 1/20 0.42
NDUFC1 O43677 1/20 0.42
NDUFA2 O43678 1/20 0.42
NDUFS5 O43920 1/20 0.42
NDUFS7 O75251 1/20 0.42
NDUFS2 O75306 1/20 0.42
NDUFS6 O75380 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11294662 1.00 ALDH1A1 (0.46) ALDH1A1TSHRBTN3A1AOC3ALOX15
SCHEMBL11262257 0.84 LTA4H (0.43) HTTLMNACYP2C19
SCHEMBL11269821 0.84 PPARG (0.44) ALDH1A1AOC3MTNR1AMTNR1BPPARD
SCHEMBL11250592 0.84 MAOB (0.46) ALDH1A1L3MBTL1PPARDPPARAPPARG
SCHEMBL11262254 0.84 LTA4H (0.43) HTTLMNACYP2C19
SCHEMBL11250596 0.84 MAOB (0.46) ALDH1A1L3MBTL1PPARDPPARAPPARG
SCHEMBL11269815 0.84 PPARG (0.44) ALDH1A1AOC3MTNR1AMTNR1BPPARD
SCHEMBL11253943 0.82 TDP1 (0.46) ALDH1A1TSHRMTNR1AL3MBTL1PPARD
SCHEMBL11253941 0.82 TDP1 (0.46) ALDH1A1TSHRMTNR1AL3MBTL1PPARD
SCHEMBL11259957 0.82 LMNA (0.51) ALDH1A1TSHRMTNR1AMTNR1BLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0046282-A2 4-Phenoxy-2-butene derivatives and their use as plant growth regulators J.T. Baker Chemical Co. (US) 1982-02-24 EP disclosed
US-4009202-A 2(OR 3)-METHYL-1-ACETOXY-4-ALKOXY (OR PHENOXY)-1,3-BUTADIENES BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) 1977-02-22 US disclosed