Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.65 |
| ▸ | MEN1 | O00255 | 5/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | ALPL | P05186 | 1/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.59 |
| ▸ | ALPI | P09923 | 1/20 | 0.59 |
| ▸ | ALPG | P10696 | 1/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | MMP14 | P50281 | 1/20 | 0.59 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.59 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | MPL | P40238 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8428508 | 0.91 | KMT2A (0.70) | MAPTKMT2AMEN1TDP1L3MBTL1 | |
| SCHEMBL8428506 | 0.91 | KMT2A (0.70) | MAPTKMT2AMEN1TDP1L3MBTL1 | |
| SCHEMBL30341069 | 0.83 | THRB (0.80) | MAPTKMT2AMEN1TDP1L3MBTL1 | |
| SCHEMBL144504 | 0.83 | MAPT (0.78) | MAPTKMT2AMEN1TDP1L3MBTL1 | |
| SCHEMBL29353711 | 0.83 | MAPT (0.78) | MAPTKMT2AMEN1TDP1L3MBTL1 | |
| SCHEMBL339399 | 0.83 | MAPT (0.78) | MAPTKMT2AMEN1TDP1L3MBTL1 | |
| SCHEMBL29378285 | 0.83 | MAPT (0.78) | MAPTKMT2AMEN1TDP1L3MBTL1 | |
| SCHEMBL16322716 | 0.81 | MAPT (0.78) | MAPTKMT2AMEN1TDP1L3MBTL1 | |
| SCHEMBL15242093 | 0.81 | MAPT (0.78) | MAPTKMT2AMEN1TDP1L3MBTL1 | |
| SCHEMBL16322715 | 0.81 | MAPT (0.78) | MAPTKMT2AMEN1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0004399-B1 | PHOTOGRAPHIC MATERIAL SUITED FOR USE IN DIFFUSION TRANSFER PHOTOGRAPHY AND METHOD OF DIFFUSION TRANSFER PHOTOGRAPHY USING SUCH MATERIAL | AGFA-GEVAERT N.V. (BE) | 1982-05-12 | — | — | EP | disclosed |
| US-4232107-A | Photographic material suited for use in diffusion transfer photography and method of diffusion transfer photography using such material | AGFA-GEVAERT N.V. (BE) | 1980-11-04 | — | — | US | disclosed |
| EP-0004399-A2 | Photographic material suited for use in diffusion transfer photography and method of diffusion transfer photography using such material | AGFA-GEVAERT N.V. (BE) | 1979-10-03 | — | — | EP | disclosed |