Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 2/20 | 0.80 |
| ▸ | PTGS2 known ✓ | P35354 | 2/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | MPL | P40238 | 1/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1096353 | 0.89 | CYP1A2 (0.76) | THRBPTPN1CYP1A2CYP2C9MAPT | |
| SCHEMBL1096355 | 0.89 | CYP1A2 (0.76) | THRBPTPN1CYP1A2CYP2C9MAPT | |
| E110 SCHEMBL29350765 | 0.89 | THRB (1.00) | THRBPTPN1CYP1A2CYP2C9MAPT | |
| E110 SCHEMBL13276157 | 0.89 | THRB (1.00) | THRBPTPN1CYP1A2CYP2C9MAPT | |
| E110 SCHEMBL142458 | 0.89 | THRB (1.00) | THRBPTPN1CYP1A2CYP2C9MAPT | |
| E110 SCHEMBL323402 | 0.89 | THRB (1.00) | THRBPTPN1CYP1A2CYP2C9MAPT | |
| SCHEMBL27866118 | 0.88 | CYP1A2 (0.74) | THRBPTPN1CYP1A2CYP2C9MAPT | |
| SCHEMBL30341067 | 0.87 | THRB (0.85) | THRBPTPN1CYP1A2CYP2C9MAPT | |
| SCHEMBL12760915 | 0.86 | THRB (0.95) | THRBPTPN1CYP1A2CYP2C9MAPT | |
| SCHEMBL3196947 | 0.85 | THRB (0.88) | THRBPTPN1CYP1A2CYP2C9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3434764-B1 | FABRIC AND HOME CARE PRODUCTS | PROCTER & GAMBLE (US) | 2026-04-08 | — | — | EP | disclosed |
| US-12338416-B2 | Fabric and home care products with cold water protease | THE PROCTER & GAMBLE COMPANY (US) | 2025-06-24 | — | — | US | disclosed |
| EP-4159833-A2 | FABRIC AND HOME CARE PRODUCTS | The Procter & Gamble Company (US) | 2023-04-05 | — | — | EP | disclosed |