Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 4/20 | 0.76 |
| ▸ | MAPT | P10636 | 9/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.78 |
| ▸ | MEN1 | O00255 | 5/20 | 0.78 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.67 |
| ▸ | ALPL | P05186 | 1/20 | 0.67 |
| ▸ | ALPI | P09923 | 1/20 | 0.67 |
| ▸ | ALPG | P10696 | 1/20 | 0.67 |
| ▸ | CASP3 | P42574 | 1/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.67 |
| ▸ | MMP14 | P50281 | 1/20 | 0.67 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.67 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.67 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.63 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29378285 | 1.00 | MAPT (0.78) | MAPTKMT2AMEN1THRBTDP1 | |
| SCHEMBL29353711 | 1.00 | MAPT (0.78) | MAPTKMT2AMEN1THRBTDP1 | |
| SCHEMBL144504 | 1.00 | MAPT (0.78) | MAPTKMT2AMEN1THRBTDP1 | |
| SCHEMBL16322715 | 0.97 | MAPT (0.78) | MAPTKMT2AMEN1THRBTDP1 | |
| SCHEMBL16322716 | 0.97 | MAPT (0.78) | MAPTKMT2AMEN1THRBTDP1 | |
| SCHEMBL30842302 | 0.89 | MAPT (0.78) | MAPTKMT2AMEN1THRBTDP1 | |
| SCHEMBL136632 | 0.89 | THRB (0.64) | MAPTKMT2AMEN1THRBTDP1 | |
| SCHEMBL29423647 | 0.89 | THRB (0.64) | MAPTKMT2AMEN1THRBTDP1 | |
| SCHEMBL11336943 | 0.87 | MAPT (0.80) | MAPTKMT2AMEN1THRBTDP1 | |
| SCHEMBL29376978 | 0.87 | MAPT (0.80) | MAPTKMT2AMEN1THRBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 161 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4528210-A2 | TRACER PROJECTILE HAVING AT LEAST ONE COLOUR CHANGE | RWS GmbH (DE) | 2025-03-26 | — | — | EP | claimed |
| WO-2015049694-A9 | TOPICAL PIGMENTORY COMPOSITION | BANERJI SANJAY (IN) | 2016-02-04 | — | — | WO | claimed |
| WO-2025084925-A1 | QUALITY CONTROL METHOD FOR CO2 CAPTURE MATERIAL | SKYTREE B.V (NL) | 2025-04-24 | — | — | WO | disclosed |
| US-20250108658-A1 | INKJET PRINTING PROCESSES FOR TEMPORARY TATTOOS | Prism Inks, Inc. (US) | 2025-04-03 | — | — | US | disclosed |
| EP-4528210-A2 | TRACER PROJECTILE HAVING AT LEAST ONE COLOUR CHANGE | RWS GmbH (DE) | 2025-03-26 | — | — | EP | disclosed |
| US-20240216253-A1 | SKIN PERFECTING COMPOSITIONS | L'OREAL (FR) | 2024-07-04 | — | — | US | disclosed |
| WO-2024144987-A1 | SKIN PERFECTING AND TIGHTENING COMPOSITIONS | L'OREAL (FR) | 2024-07-04 | — | — | WO | disclosed |
| US-20240216254-A1 | SKIN PERFECTING AND TIGHTENING COMPOSITIONS | L'OREAL (FR) | 2024-07-04 | — | — | US | disclosed |
| EP-3172266-B1 | METHOD FOR MODIFYING THE SURFACE PROPERTIES OF ELASTOMER CELLULAR FOAMS | UNIV STRASBOURG (FR) | 2024-07-03 | — | — | EP | disclosed |
| US-12011494-B2 | Skin perfecting cosmetic compositions and methods of use | L'OREAL (FR) | 2024-06-18 | — | — | US | disclosed |
| US-20230414512-A1 | Dermal Delivery Compositions Comprising Active Agent-Calcium Phosphate Particle Complexes and Methods of Using the Same | LABORATORY SKIN CARE, INC. | 2023-12-28 | — | — | US | disclosed |
| WO-2003051319-A1 | CLEANING PRODUCTS BASED ON MICROEMULSIONS THAT CONTAIN OIL | BEIERSDORF AG (DE) | 2003-06-26 | — | — | WO | disclosed |
| WO-2003045349-A2 | ITCH-RELIEVING COSMETIC AND DERMATOLOGICAL PREPARATIONS | BEIERSDORF AG (DE) | 2003-06-05 | — | — | WO | disclosed |
| EP-1310235-A2 | Emulsifier-free cosmetic and dermatological sunscreen formulations comprising hydroxybenzophenones | Beiersdorf AG (DE) | 2003-05-14 | — | — | EP | disclosed |
| US-20020189031-A1 | Use of salts for improving the absorption qualities of anionic direct dyes | WELLA AKTIENGESELLSCHAFT (DE) | 2002-12-19 | — | — | US | disclosed |
| EP-1083861-A1 | HYDROUS COSMETIC OR PHARMACEUTICAL STICKS | Beiersdorf Aktiengesellschaft (DE) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999065454-A1 | HYDROUS COSMETIC OR PHARMACEUTICAL STICKS | BEIERSDORF AG (DE) | 1999-12-23 | — | — | WO | disclosed |
| US-5936016-A | SPIRO(INDOLINE(2,3')-NAPHTHOXAZINES) HAVING SPECIFIED SUBSTITUENT IN THE 6' POSITION; OPHTHALMIC OPTICS AND LENSES | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 1999-08-10 | — | — | US | disclosed |
| US-5463034-A | Containing basic and/or cationic groups | WOLFF WALSRODE AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |
| US-5015263-A | Composition for coloring skin and method | CLAIROL INCORPORATED (US) | 1991-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12011494-B2 | Skin perfecting cosmetic compositions and methods of use | CUTA, DSG1, SMURF1 | THRB 2742/4885MAPT 3420/4885KMT2A 1248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.