Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 12/20 | 0.55 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11295469 | 0.90 | MTNR1A (0.53) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL11291111 | 0.81 | MTNR1A (0.39) | MTNR1AMTNR1BCA1CA2SMN1; SMN2 | |
| SCHEMBL14196062 | 0.77 | AR (0.44) | MTNR1AMTNR1BCA1CA2 | |
| SCHEMBL5751441 | 0.77 | MTNR1A (0.46) | MTNR1AMTNR1BSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11305840 | 0.77 | DRD2 (0.44) | — | |
| SCHEMBL11312993 | 0.76 | MEN1 (0.41) | MTNR1AMTNR1BACHESMN1; SMN2NQO2 | |
| SCHEMBL11310753 | 0.76 | MTNR1A (0.50) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL5780440 | 0.75 | MCHR2 (0.35) | MTNR1AMTNR1BCA1CA2 | |
| Hydrochloric Acid SCHEMBL11316278 | 0.75 | MEN1 (0.40) | MTNR1AMTNR1BACHESMN1; SMN2NQO2 | |
| SCHEMBL6400837 | 0.75 | ALDH1A1 (0.40) | CA1CA2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0005821-B1 | INDANAMINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Hokuriku Pharmaceutical Co.,Ltd (JP) | 1982-12-08 | — | — | EP | disclosed |
| EP-0005821-A1 | Indanamine derivatives, process for their preparation and medicaments containing them | Hokuriku Pharmaceutical Co.,Ltd (JP) | 1979-12-12 | — | — | EP | disclosed |