SCHEMBL11295295

SCHEMBL11295295

CCCCCCSC(=S)SCCC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.39
HSD17B10 Q99714 2/20 0.39
CES2 O00748 1/20 0.39
GMNN O75496 1/20 0.39
TP53 P04637 1/20 0.39
POLB P06746 1/20 0.39
MAPT P10636 1/20 0.39
CYP2C9 P11712 1/20 0.39
BLM P54132 1/20 0.39
TSHR P16473 2/20 0.38
NOS3 P29474 2/20 0.38
NOS1 P29475 2/20 0.38
NOS2 P35228 2/20 0.38
ACHE P22303 2/20 0.37
MGLL Q99685 1/20 0.36
LMNA P02545 2/20 0.36
ALDH1A1 P00352 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14895470 1.00 THRB (0.39) THRBHSD17B10CES2GMNNTP53
SCHEMBL10571256 0.95 THRB (0.42) THRBHSD17B10CES2GMNNTP53
SCHEMBL11170048 0.95 THRB (0.42) THRBHSD17B10CES2GMNNTP53
SCHEMBL35363 0.95 THRB (0.42) THRBHSD17B10CES2GMNNTP53
SCHEMBL11441821 0.95 THRB (0.42) THRBHSD17B10CES2GMNNTP53
SCHEMBL35565 0.95 THRB (0.42) THRBHSD17B10CES2GMNNTP53
SCHEMBL11289157 0.95 THRB (0.42) THRBHSD17B10CES2GMNNTP53
SCHEMBL35803 0.95 THRB (0.42) THRBHSD17B10CES2GMNNTP53
SCHEMBL10569638 0.93 NOS3 (0.44) THRBHSD17B10CES2GMNNTP53
SCHEMBL1441085 0.93 NOS3 (0.44) THRBHSD17B10CES2GMNNTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4316797-A FROTH FLOTATION USING AN AROMATIC OIL AND ALLYL GUTYL TRITHIOCARBONATE PHILLIPS PETROLEUM COMPANY (US) 1982-02-23 US disclosed