SCHEMBL35565

SCHEMBL35565

CCCCCCSC(=S)SCCCCCC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.42
TSHR P16473 2/20 0.42
HSD17B10 Q99714 2/20 0.41
CES2 O00748 2/20 0.41
GMNN O75496 1/20 0.41
TP53 P04637 1/20 0.41
POLB P06746 1/20 0.41
MAPT P10636 1/20 0.41
CYP2C9 P11712 1/20 0.41
BLM P54132 1/20 0.41
NOS3 P29474 1/20 0.41
NOS1 P29475 1/20 0.41
NOS2 P35228 1/20 0.41
LMNA P02545 2/20 0.39
ALDH1A1 P00352 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
ACHE P22303 2/20 0.39
MGLL Q99685 1/20 0.39
CA12 O43570 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11170048 1.00 THRB (0.42) THRBTSHRHSD17B10CES2GMNN
SCHEMBL11289157 1.00 THRB (0.42) THRBTSHRHSD17B10CES2GMNN
SCHEMBL11441821 1.00 THRB (0.42) THRBTSHRHSD17B10CES2GMNN
SCHEMBL35803 1.00 THRB (0.42) THRBTSHRHSD17B10CES2GMNN
SCHEMBL35363 1.00 THRB (0.42) THRBTSHRHSD17B10CES2GMNN
SCHEMBL10571256 1.00 THRB (0.42) THRBTSHRHSD17B10CES2GMNN
SCHEMBL10569638 0.97 NOS3 (0.44) THRBTSHRHSD17B10CES2GMNN
SCHEMBL1441085 0.97 NOS3 (0.44) THRBTSHRHSD17B10CES2GMNN
SCHEMBL11295295 0.95 THRB (0.39) THRBTSHRHSD17B10CES2GMNN
SCHEMBL14895470 0.95 THRB (0.39) THRBTSHRHSD17B10CES2GMNN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10871595-B2 Polymers and nanogel materials and methods for making and using the same JOHNSON & JOHNSON VISION CARE, INC. (US) 2020-12-22 US disclosed
US-20200049858-A1 POLYMERS AND NANOGEL MATERIALS AND METHODS FOR MAKING AND USING THE SAME JOHNSON & JOHNSON VISION CARE (US) 2020-02-13 US disclosed
US-10301465-B2 Non-reactive, hydrophilic polymers having terminal siloxanes and methods for making and using the same JOHNSON & JOHNSON VISION CARE, INC. (US) 2019-05-28 US disclosed
US-20180341044-A1 POLYMERS AND NANOGEL MATERIALS AND METHODS FOR MAKING AND USING THE SAME JOHNSON & JOHNSON VISION CARE (US) 2018-11-29 US disclosed
EP-3401342-A1 POLYMERS AND NANOGEL MATERIALS AND METHODS FOR MAKING AND USING THE SAME Johnson & Johnson Vision Care, Inc. (US) 2018-11-14 EP disclosed
EP-2566911-B1 NON-REACTIVE, HYDROPHILIC POLYMERS HAVING TERMINAL SILOXANES AND USES OF THE SAME JOHNSON & JOHNSON VISION CARE (US) 2018-10-24 EP disclosed
US-10073192-B2 Polymers and nanogel materials and methods for making and using the same JOHNSON & JOHNSON VISION CARE, INC. (US) 2018-09-11 US disclosed
EP-2855544-B1 POLYMERS AND NANOGEL MATERIALS AND METHODS FOR MAKING AND USING THE SAME JOHNSON & JOHNSON VISION CARE (US) 2018-06-20 EP disclosed
US-20180044518-A1 NON-REACTIVE, HYDROPHILIC POLYMERS HAVING TERMINAL SILOXANES AND METHODS FOR MAKING AND USING THE SAME JOHNSON & JOHNSON VISION CARE (US) 2018-02-15 US disclosed
US-9815979-B2 Non-reactive, hydrophilic polymers having terminal siloxanes and methods for making and using the same JOHNSON & JOHNSON VISION CARE, INC. (US) 2017-11-14 US disclosed
CN-104334596-A Polymer and nanogel materials and methods of making and using the same JOHNSON & JOHNSON VISION CARE 2015-02-04 CN disclosed
WO-2013177523-A2 POLYMERS AND NANOGEL MATERIALS AND METHODS FOR MAKING AND USING THE SAME JOHNSON & JOHNSON VISION CARE, INC. (US) 2013-11-28 WO disclosed
US-20130317131-A1 POLYMERS AND NANOGEL MATERIALS AND METHODS FOR MAKING AND USING THE SAME JOHNSON & JOHNSON VISION CARE, INC. (US) 2013-11-28 US disclosed
WO-2013176886-A2 POLYMERS AND NANOGEL MATERIALS AND METHODS FOR MAKING AND USING THE SAME JOHNSON & JOHNSON VISION CARE, INC. (US) 2013-11-28 WO disclosed
EP-2566911-A1 NON-REACTIVE, HYDROPHILIC POLYMERS HAVING TERMINAL SILOXANES AND USES OF THE SAME Johnson & Johnson Vision Care, Inc. (US) 2013-03-13 EP disclosed
US-20110275734-A1 NON-REACTIVE, HYDROPHILIC POLYMERS HAVING TERMINAL SILOXANES AND METHODS FOR MAKING AND USING THE SAME JOHNSON & JOHNSON VISION CARE, INC. 2011-11-10 US disclosed
WO-2011140318-A1 NON-REACTIVE, HYDROPHILIC POLYMERS HAVING TERMINAL SILOXANES AND USES OF THE SAME JOHNSON & JOHNSON VISION CARE, INC. (US) 2011-11-10 WO disclosed
US-4215140-A Cyanomethyl alkyl trithiocarbonates as insecticidal agents ALLIED CHEMICAL CORPORATION (US) 1980-07-29 US disclosed
US-4197311-A CONTROL OF INSECTS AND ACARINA, ALSO OVICIDAL USE OF DITHIOCARBONATES AMERICAN CYANAMID COMPANY (US) 1980-04-08 US disclosed
US-3976769-A INSECTICIDE AIRWICK INDUSTRIES, INC. (US) 1976-08-24 US disclosed