Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 4/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.37 |
| ▸ | HRH2 | P25021 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | HTR5A | P47898 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9619657 | 0.90 | CYP2D6 (0.50) | CYP2D6KCNH2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21072047 | 0.83 | MEN1 (0.40) | CYP2D6KCNH2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5411041 | 0.79 | SCN1A (0.50) | CYP2D6KCNH2SLC6A2SLC6A4SLC6A3 | |
| Triethylene Glycol SCHEMBL4815749 | 0.77 | KMT2A (0.41) | CYP2D6KCNH2MEN1KMT2ATRPA1 | |
| SCHEMBL11297660 | 0.77 | LMNA (0.40) | CYP2D6KCNH2SLC6A2MEN1KMT2A | |
| Di(Hydroxyethyl)Ether SCHEMBL11297509 | 0.75 | TRPA1 (0.42) | CYP2D6KCNH2MEN1KMT2ATRPA1 | |
| SCHEMBL13311313 | 0.73 | GLS (0.43) | CYP2D6KCNH2MEN1KMT2ACHRM2 | |
| SCHEMBL431888 | 0.72 | SCN1A (0.41) | CYP2D6KCNH2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9750485 | 0.72 | TAAR1 (0.42) | CYP2D6KCNH2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8905052 | 0.72 | TRPA1 (0.50) | KCNH2TRPA1CHRM2ADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4343732-A | HEAT AND WEATHER RESISTANCE, BISPHENOL PHOSPHATE STABILIZER | AJINOMOTO COMPANY INCORPORATED (JP) | 1982-08-10 | — | — | US | disclosed |