Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL957645 | 0.88 | ABCB11 (0.73) | MAPK1MAPTABCB11LMNAKMT2A | |
| SCHEMBL11298604 | 0.88 | MAPT (0.76) | MAPK1MAPTABCB11LMNATDP1 | |
| SCHEMBL11300087 | 0.87 | MAPK1 (0.65) | MAPK1MAPTABCB11LMNAL3MBTL1 | |
| SCHEMBL957321 | 0.86 | MAPT (0.78) | MAPK1MAPTABCB11LMNATDP1 | |
| SCHEMBL11292121 | 0.86 | MAPT (0.78) | MAPK1MAPTABCB11LMNATDP1 | |
| SCHEMBL956571 | 0.85 | LMNA (0.60) | MAPK1MAPTABCB11LMNAL3MBTL1 | |
| SCHEMBL11288224 | 0.85 | MAPT (0.80) | MAPK1MAPTABCB11LMNAL3MBTL1 | |
| SCHEMBL11289517 | 0.85 | MAPK1 (0.58) | MAPK1MAPTABCB11LMNAL3MBTL1 | |
| SCHEMBL14769764 | 0.84 | MAPT (0.82) | MAPK1MAPTABCB11LMNAL3MBTL1 | |
| SCHEMBL11288785 | 0.84 | MAPT (0.70) | MAPK1MAPTABCB11LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337267-A | HYPOKETONEMIC, HYPOGLYCEMIC, ANTIDIABETIC | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-06-29 | — | — | US | disclosed |