Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.78 |
| ▸ | LMNA | P02545 | 3/20 | 0.78 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.78 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.78 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.46 |
| ▸ | P4HB | P07237 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11292121 | 1.00 | MAPT (0.78) | MAPTLMNAMAPK1ABCB11TDP1 | |
| SCHEMBL11298604 | 0.99 | MAPT (0.76) | MAPTLMNAMAPK1ABCB11TDP1 | |
| SCHEMBL11288785 | 0.95 | MAPT (0.70) | MAPTLMNAMAPK1ABCB11TDP1 | |
| SCHEMBL11292129 | 0.91 | LMNA (0.64) | MAPTLMNAMAPK1ABCB11TDP1 | |
| SCHEMBL14769764 | 0.90 | MAPT (0.82) | MAPTLMNAMAPK1ABCB11GAA | |
| SCHEMBL11288224 | 0.88 | MAPT (0.80) | MAPTLMNAMAPK1ABCB11GAA | |
| SCHEMBL11297622 | 0.88 | ABCB11 (0.78) | MAPTLMNAMAPK1ABCB11SMN1; SMN2 | |
| SCHEMBL955245 | 0.88 | ABCB11 (0.78) | MAPTLMNAMAPK1ABCB11SMN1; SMN2 | |
| SCHEMBL1578568 | 0.88 | MAPT (0.78) | MAPTLMNAMAPK1ABCB11GAA | |
| Etomoxir SCHEMBL49075 | 0.88 | ABCB11 (1.00) | MAPTLMNAMAPK1ABCB11GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200330400-A1 | METHODS FOR THE TREATMENT OF CANCER USING COENZYME Q10 AND FATTY ACID METABOLISM INHIBITORS | BERG LLC | 2020-10-22 | — | — | US | claimed |
| WO-2017161205-A1 | METHODS FOR THE TREATMENT OF CANCER USING COENZYME Q10 AND FATTY ACID METABOLISM INHIBITORS | BERG LLC (US) | 2017-09-21 | — | — | WO | claimed |
| WO-2014018801-A1 | DIAGNOSIS AND TREATMENT OF CANCER USING DIFFERENTIALLY EXPRESSED STARVATION MARKERS | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2014-01-30 | — | — | WO | claimed |
| WO-2013071029-A1 | METHODS AND PRODUCTS FOR GENERATING OILS | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2013-05-16 | — | — | WO | claimed |
| US-20130056683-A1 | COMPOSITIONS AND METHODS FOR PROMOTING FATTY ACID PRODUCTION IN PLANTS | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2013-03-07 | — | — | US | claimed |
| WO-2012135632-A2 | METHODS OF TREATING A SUBJECT HAVING BEEN EXPOSED TO A CATASTROPHIC EVENT | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2012-10-04 | — | — | WO | claimed |
| EP-2486140-A2 | COMPOSITIONS AND METHODS FOR PROMOTING FATTY ACID PRODUCTION IN PLANTS | Regents of the University of Colorado (US) | 2012-08-15 | — | — | EP | claimed |
| WO-2011043806-A2 | COMPOSITIONS AND METHODS FOR PROMOTING FATTY ACID PRODUCTION IN PLANTS | REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2011-04-14 | — | — | WO | claimed |
| US-20110078946-A1 | COMPOSITIONS AND METHODS FOR PROMOTING FATTY ACID PRODUCTION IN PLANTS | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE | 2011-04-07 | — | — | US | claimed |
| EP-1275390-B1 | Medicament for treatment of heart failure | WOLF HORST P O (DE) | 2005-11-02 | — | — | EP | claimed |
| US-5739159-A | Medicaments for the treatment of cardiac insufficiency | WOLF HORST (DE) | 1998-04-14 | — | — | US | claimed |
| EP-0231367-B1 | USE OF OXIRANCARBOXYLIC ACIDS FOR THE TREATMENT OF HYPERLIPEMIA | Wolf, Horst P.O., Dr. (DE) | 1991-07-24 | — | — | EP | claimed |
| US-20200330400-A1 | METHODS FOR THE TREATMENT OF CANCER USING COENZYME Q10 AND FATTY ACID METABOLISM INHIBITORS | BERG LLC | 2020-10-22 | — | — | US | disclosed |
| US-10041096-B2 | Methods and products for generating oils | TEXAS A & M UNIV SYS (US) | 2018-08-07 | — | — | US | disclosed |
| WO-2017161205-A1 | METHODS FOR THE TREATMENT OF CANCER USING COENZYME Q10 AND FATTY ACID METABOLISM INHIBITORS | BERG LLC (US) | 2017-09-21 | — | — | WO | disclosed |
| US-20150231237-A1 | METHODS AND PRODUCTS FOR TREATING PROLIFERATIVE DISEASES | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2015-08-20 | — | — | US | disclosed |
| US-20020198382-A1 | Oxiran carboxylic acids for the treatment of diabetes | HORST P.O. WOLF (DE) | 2002-12-26 | — | — | US | disclosed |
| US-6013666-A | ANTIDIABETIC AGENTS; SIDE EFFECT REDUCTION | Jew, Sang Sup (KR) | 2000-01-11 | — | — | US | disclosed |
| US-5739159-A | Medicaments for the treatment of cardiac insufficiency | WOLF HORST (DE) | 1998-04-14 | — | — | US | disclosed |
| WO-1998000422-A1 | OXIRANE CARBOXYLIC ACID DERIVATIVE AND ITS MANUFACTURING METHOD | JEW SANG SUP (KR) | 1998-01-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020198382-A1 | Oxiran carboxylic acids for the treatment of diabetes | GPR119, SLC5A2, SLC2A4 | MAPT 4759/4885LMNA 3609/4885MAPK1 1907/4885 |
| US-20200330400-A1 | METHODS FOR THE TREATMENT OF CANCER USING COENZYME Q10 AND FATTY ACID METABOLISM INHIBITORS | CPT1B, CPT2, CPT1A | MAPT 2554/4885LMNA 1667/4885MAPK1 3874/4885 |
| US-10041096-B2 | Methods and products for generating oils | LIPE, FASN, LIPC | MAPT 4545/4885LMNA 4267/4885MAPK1 4402/4885 |
| US-20150231237-A1 | METHODS AND PRODUCTS FOR TREATING PROLIFERATIVE DISEASES | BECN1, G6PD, VHL | MAPT 2123/4885LMNA 3405/4885MAPK1 980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.