SCHEMBL1129570

SCHEMBL1129570

Cc1cn([C@H]2CO[C@@H](CO)O2)c(=O)[nH]c1=O

nearest known ligand 0.60

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.55
ALB P02768 2/20 0.55
BLM P54132 2/20 0.55
ALDH1A1 P00352 1/20 0.55
POLB P06746 1/20 0.55
ADRA1A P35348 1/20 0.55
TK1 P04183 6/20 0.55
TSHR P16473 2/20 0.53
PKM P14618 1/20 0.53
PMP22 Q01453 1/20 0.53
CYP2D6 P10635 1/20 0.53
DHFR P00374 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6314490 1.00 LMNA (0.55) LMNAALBBLMALDH1A1POLB
SCHEMBL7701755 1.00 LMNA (0.55) LMNAALBBLMALDH1A1POLB
SCHEMBL1130181 1.00 LMNA (0.55) LMNAALBBLMALDH1A1POLB
SCHEMBL6760136 1.00 LMNA (0.55) LMNAALBBLMALDH1A1POLB
SCHEMBL1129572 1.00 LMNA (0.55) LMNAALBBLMALDH1A1POLB
SCHEMBL14580339 0.87 TK1 (0.48) LMNAALBBLMALDH1A1POLB
SCHEMBL2920441 0.86 TK1 (0.52) LMNATK1
SCHEMBL2920443 0.86 TK1 (0.52) LMNATK1
SCHEMBL6753208 0.84 SMN1; SMN2 (0.54) LMNABLMALDH1A1POLBADRA1A
SCHEMBL6752642 0.84 LMNA (0.60) LMNAADRA1ATK1TSHRPMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144879-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS AI-BIOPHARMA (FR) 2026-05-28 US claimed
US-20240139325-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS AI-BIOPHARMA (FR) 2024-05-02 US claimed
EP-4045504-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS Ai-biopharma (FR) 2022-08-24 EP claimed
CN-114901657-A Antiviral and liver-targeting drugs 人工智能生物制药公司 2022-08-12 CN claimed
EP-1693373-A1 Enantiomerically pure beta-D-(-)-dioxolane-nucleosides EMORY UNIVERSITY (US) 2006-08-23 EP claimed
EP-1600448-A2 Enantiomerically pure beta-D-(-)-Dioxolane-Nucleosides University of Georgia Research Foundation, Inc. (US) 2005-11-30 EP claimed
EP-0562009-A4 ENANTIOMERICALLY PURE -G(B)-D-(-)-DIOXOLANE-NUCLEOSIDES 1993-11-24 EP claimed
EP-0562009-A1 ENANTIOMERICALLY PURE $g(b)-D-(-)-DIOXOLANE-NUCLEOSIDES THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1993-09-29 EP claimed
US-5179104-A Process for the preparation of enantiomerically pure β-D-(-)-dioxolane-nucleosides UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1993-01-12 US claimed
WO-1992010497-A1 ENANTIOMERICALLY PURE β-D-(-)-DIOXOLANE-NUCLEOSIDES UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1992-06-25 WO claimed
US-20260144879-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS AI-BIOPHARMA (FR) 2026-05-28 US disclosed
EP-2841109-B1 PRODRUGS OF HYDROXYL-COMPRISING DRUGS ASCENDIS PHARMA AS (DK) 2026-04-15 EP disclosed
US-12539332-B2 Anti-viral and hepatic-targeted drugs A-BIOPHARMA (FR) 2026-02-03 US disclosed
EP-4611757-A1 VIRAL PROPHYLAXIS TREATMENT METHODS AND PRE-EXPOSURE PROPHYLAXIS KITS Ramirez, Christina, M. (US) 2025-09-10 EP disclosed
US-12383558-B2 Antiviral JAK inhibitors useful in treating or preventing retroviral and other viral infections EMORY UNIVERSITY (US) 2025-08-12 US disclosed
US-5248776-A Multistage reaction with sulfiding, cyclization and oxidative cleavage UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1993-09-28 US disclosed
US-5179104-A Process for the preparation of enantiomerically pure β-D-(-)-dioxolane-nucleosides UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1993-01-12 US disclosed
WO-1992014729-A1 ANTIVIRAL 1,3-DIOXOLANE NUCLEOSIDES AND SYNTHESIS THEREOF EMORY UNIVERSITY (US) 1992-09-03 WO disclosed
WO-1992010496-A1 ENANTIOMERICALLY PURE β-L-(-)-1,3-OXATHIOLANE NUCLEOSIDES UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1992-06-25 WO disclosed
WO-1992010497-A1 ENANTIOMERICALLY PURE β-D-(-)-DIOXOLANE-NUCLEOSIDES UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1992-06-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12539332-B2 Anti-viral and hepatic-targeted drugs HAVCR2, NR1H4, NR1H3 LMNA 1280/4885ALB 3076/4885BLM 4047/4885
US-20260144879-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS HAVCR2, NR1H4, NR1H3 LMNA 1661/4885ALB 3481/4885BLM 4147/4885
US-12383558-B2 Antiviral JAK inhibitors useful in treating or preventing retroviral and other viral infections JAK1, JAK3, PNP LMNA 4334/4885ALB 3655/4885BLM 4565/4885
US-20240139325-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS SLC10A1, HAVCR2, HDGF LMNA 2736/4885ALB 315/4885BLM 3381/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.