SCHEMBL1129610

SCHEMBL1129610

Cc1cc(O)c(C(=O)O)cc1C(C)(C)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
MCL1 Q07820 4/20 0.44
RXRA P19793 1/20 0.44
ESR1 P03372 2/20 0.42
ESR2 Q92731 2/20 0.42
CSNK2A1 P68400 1/20 0.42
CYP3A4 P08684 1/20 0.41
ACMSD Q8TDX5 3/20 0.40
HNF4A P41235 2/20 0.40
DHFR P00374 1/20 0.40
CNR1 P21554 2/20 0.39
CNR2 P34972 2/20 0.39
KDM4E B2RXH2 2/20 0.39
HPGD P15428 2/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
HMGB1 P09429 1/20 0.39
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11757570 0.87 ALDH1A1 (0.43) ALDH1A1MCL1ESR1ESR2CSNK2A1
SCHEMBL9757833 0.82 ESR1 (0.53) ALDH1A1RXRAESR1ESR2CYP3A4
SCHEMBL5075361 0.80 CA12 (0.47) ALDH1A1MCL1CSNK2A1CYP3A4CA12
SCHEMBL9253188 0.80 ALDH1A1 (0.46) ALDH1A1MCL1CSNK2A1CYP3A4KDM4E
SCHEMBL8367509 0.77 ESR1 (0.41) ALDH1A1RXRAESR1ESR2CYP3A4
SCHEMBL10723064 0.76 MCL1 (0.52) ALDH1A1MCL1ESR1ESR2CSNK2A1
SCHEMBL9769854 0.76 GRIN2D (0.47) ALDH1A1MCL1ESR1ESR2CYP3A4
SCHEMBL5885487 0.76 ALDH1A1 (0.53) ALDH1A1ESR1ESR2CYP3A4ACMSD
SCHEMBL5442998 0.76 ESR1 (0.53) ALDH1A1MCL1ESR1ESR2CSNK2A1
SCHEMBL9351447 0.75 LMNA (0.45) ALDH1A1ESR1ESR2CYP3A4CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8283287-B2 Thermosensitive recording material RICOH COMPANY, LTD. (JP) 2012-10-09 US disclosed
EP-2036737-B1 Thermosensitive recording material RICOH CO LTD (JP) 2011-02-16 EP disclosed
US-20090075817-A1 THERMOSENSITIVE RECORDING MATERIAL RICOH COMPANY, LTD. (JP) 2009-03-19 US disclosed
EP-2036737-A1 Thermosensitive recording material Ricoh Company, Ltd. (JP) 2009-03-18 EP disclosed
EP-0338808-B1 Alkyl salicylate resin for carbonless copy paper and imaging use SCHENECTADY INT INC (US) 1995-08-23 EP disclosed
EP-0482668-B1 HEAT SENSITIVE RECORDING MATERIAL KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1993-08-04 EP disclosed
US-5187143-A Thermographic mixture of basic leuco dye and color developer comprising a zinc salt of terephthaldehydic acid or a composite salt also containing an aromatic acid KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1993-02-16 US disclosed
EP-0482668-A1 Heat sensitive recording material KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1992-04-29 EP disclosed
US-5017546-A Metallized phenolic resins SCHENECTADY INTERNATIONAL, INC. 1991-05-21 US disclosed
US-4999333-A For facsimile and thermal printing FUJI PHOTO FILM CO., LTD. (JP) 1991-03-12 US disclosed
US-4920091-A CONTAINING SALICYLIC ACID DERIVATIVE AS ELECTRON ACCEPTING COLOR DEVELOPER; STABLE IMAGES FUJI PHOTO FILM CO., LTD. (JP) 1990-04-24 US disclosed
US-4918047-A CONTAINING OXYSALICYLIC ACID DERIVATIVE AND ZINC COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1990-04-17 US disclosed
EP-0338808-A2 Alkyl salicylate resin for carbonless copy paper and imaging use SCHENECTADY INTERNATIONAL, INC. (US) 1989-10-25 EP disclosed
EP-0253666-A2 Heat-sensitive recording material containing dye-forming components FUJI PHOTO FILM CO., LTD. (JP) 1988-01-20 EP disclosed
US-4134847-A HOMOGENIZING AN AROMATIC CARBOXYLIC ACID-POLYMER-METAL CARBONATE OR OXIDE MELT KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1979-01-16 US disclosed
US-4046941-A PRESSURE SENSITIVE COPYING SANKO CHEMICAL COMPANY LTD. (JA) 1977-09-06 US disclosed