Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL2 | P60568 | 2/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | ACR | P10323 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | TYK2 | P29597 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11254846 | 0.91 | EPHX2 (0.46) | IL2EPHX2TRPV1L3MBTL1MEN1 | |
| SCHEMBL11291758 | 0.89 | IL2 (0.61) | IL2L3MBTL1MEN1KMT2ATRPA1 | |
| SCHEMBL11291418 | 0.87 | MEN1 (0.54) | L3MBTL1MEN1KMT2ACYP1A2TP53 | |
| SCHEMBL11295953 | 0.87 | EPHX2 (0.49) | EPHX2TRPV1L3MBTL1MEN1KMT2A | |
| SCHEMBL11300373 | 0.87 | RAB9A (0.56) | IL2EPHX2TRPV1L3MBTL1MEN1 | |
| SCHEMBL11297511 | 0.86 | L3MBTL1 (0.58) | L3MBTL1MEN1KMT2ATP53SMN1; SMN2 | |
| SCHEMBL11293799 | 0.86 | MEN1 (0.52) | IL2L3MBTL1MEN1KMT2AFAAH | |
| SCHEMBL11264322 | 0.84 | GAA (0.52) | IL2EPHX2TRPV1L3MBTL1MEN1 | |
| SCHEMBL11296494 | 0.79 | MEN1 (0.50) | IL2L3MBTL1MEN1KMT2ACYP1A2 | |
| SCHEMBL11261749 | 0.78 | RAB9A (0.46) | EPHX2TRPV1L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322429-A | Isoxazolylbenzamides as insecticides | ELI LILLY AND COMPANY (US) | 1982-03-30 | — | — | US | claimed |