Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL957645 | 0.91 | ABCB11 (0.73) | ABCB11LMNAMAPTMAPK1HRH3 | |
| SCHEMBL11298734 | 0.87 | ABCB11 (0.59) | ABCB11LMNAMAPTMAPK1HRH3 | |
| SCHEMBL11294309 | 0.85 | LMNA (0.82) | ABCB11LMNAMAPTMAPK1HRH3 | |
| SCHEMBL11274582 | 0.85 | ABCB11 (0.53) | ABCB11LMNAMAPTMAPK1PPARG | |
| SCHEMBL6260288 | 0.83 | KDM4E (0.51) | ABCB11LMNAMAPTMAPK1HRH3 | |
| SCHEMBL11297445 | 0.82 | HRH3 (0.50) | ABCB11LMNAMAPTMAPK1HRH3 | |
| SCHEMBL11292589 | 0.81 | LMNA (0.65) | ABCB11LMNAMAPTMAPK1KDM4E | |
| SCHEMBL11022024 | 0.81 | ABCB11 (0.49) | ABCB11LMNAMAPTMAPK1HRH3 | |
| SCHEMBL7431046 | 0.81 | ABCB11 (0.49) | ABCB11LMNAMAPTMAPK1HRH3 | |
| SCHEMBL11295685 | 0.80 | MAPK1 (0.66) | ABCB11LMNAMAPTMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337267-A | HYPOKETONEMIC, HYPOGLYCEMIC, ANTIDIABETIC | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-06-29 | — | — | US | disclosed |