Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5933784 | 0.78 | CYP3A4 (0.47) | LMNAALDH1A1ALOX15CYP3A4TSHR | |
| SCHEMBL116422 | 0.74 | CA1 (0.43) | LMNACYP3A4TSHRMAPTNPSR1 | |
| SCHEMBL11464966 | 0.73 | CYP3A4 (0.58) | LMNAALDH1A1ALOX15CYP3A4TSHR | |
| SCHEMBL9242550 | 0.69 | BLM (0.39) | LMNACYP3A4TSHRMAPTNPSR1 | |
| SCHEMBL9011105 | 0.66 | CYP1A1 (0.41) | LMNAALDH1A1ALOX15CYP3A4TSHR | |
| SCHEMBL11061618 | 0.65 | ALDH1A1 (0.57) | LMNAALDH1A1ALOX15CYP3A4TSHR | |
| SCHEMBL11766120 | 0.64 | CYP3A4 (0.42) | LMNAALDH1A1CYP3A4TSHRCYP1A1 | |
| SCHEMBL8523765 | 0.64 | CNR2 (0.39) | — | |
| SCHEMBL19904758 | 0.64 | CYP3A4 (0.50) | CYP3A4 | |
| SCHEMBL11109918 | 0.63 | SRC (0.54) | ALDH1A1CYP3A4TSHRCYP1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0024649-B1 | 2,2-DICHLOROCYCLOPROPYL-METHYL-PHOSPHORIC ACID DERIVATIVES, PROCESS FOR PREPARING THEM AND THEIR USE IN COMBATING PESTS | BASF Aktiengesellschaft (DE) | 1982-08-11 | — | — | EP | claimed |
| US-4296108-A | PESTICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1981-10-20 | — | — | US | claimed |