Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CYP1A1 | P04798 | 6/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | STS | P08842 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30412917 | 0.86 | CYP3A4 (0.53) | ALDH1A1CYP3A4HSD17B10TSHRLMNA | |
| Temefos SCHEMBL23303378 | 0.86 | LMNA (0.53) | ALDH1A1CYP3A4HSD17B10TSHRLMNA | |
| Temefos SCHEMBL44105 | 0.86 | LMNA (0.53) | ALDH1A1CYP3A4HSD17B10TSHRLMNA | |
| Temefos SCHEMBL6388031 | 0.84 | LMNA (0.51) | ALDH1A1CYP3A4HSD17B10TSHRLMNA | |
| Temefos SCHEMBL8741692 | 0.84 | LMNA (0.51) | ALDH1A1CYP3A4HSD17B10TSHRLMNA | |
| Temefos SCHEMBL10455340 | 0.79 | LMNA (0.47) | ALDH1A1CYP3A4HSD17B10TSHRLMNA | |
| Temefos SCHEMBL15553439 | 0.79 | LMNA (0.51) | ALDH1A1CYP3A4HSD17B10TSHRLMNA | |
| SCHEMBL10937105 | 0.79 | ALDH1A1 (0.55) | ALDH1A1CYP3A4HSD17B10TSHRLMNA | |
| SCHEMBL8830439 | 0.78 | CYP1A1 (0.39) | ALDH1A1CYP3A4HSD17B10TSHRLMNA | |
| SCHEMBL11252416 | 0.78 | ALDH1A1 (0.55) | ALDH1A1CYP3A4HSD17B10TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4423028-A | INSECTICIDES, O-(4-METHYLTHIOPHENYL)-O,O-DIMETHYLPHOSPHOROTHIOATE | STAUFFER CHEMICAL COMPANY (US) | 1983-12-27 | — | — | US | claimed |
| CN-105532718-A | Ultralow-volume spraying agent containing fenthion and application thereof | JINAN SHUNHAO BIOTECHNOLOGY CO LTD | 2016-05-04 | — | — | CN | disclosed |
| US-4448733-A | FROM ALKYLMERCAPTO-SUBSTITUTED PHENYLPHOSPHORIC ACID ESTERS IN AN APROTIC, ACID-CONTAINING SOLVENT | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1984-05-15 | — | — | US | disclosed |
| US-4423028-A | INSECTICIDES, O-(4-METHYLTHIOPHENYL)-O,O-DIMETHYLPHOSPHOROTHIOATE | STAUFFER CHEMICAL COMPANY (US) | 1983-12-27 | — | — | US | disclosed |
| US-4423028-A | INSECTICIDES, O-(4-METHYLTHIOPHENYL)-O,O-DIMETHYLPHOSPHOROTHIOATE | STAUFFER CHEMICAL COMPANY (US) | 1983-12-27 | — | — | US | disclosed |
| EP-0062255-A2 | Preparation of alkylsulfinyl-substituted organophosphoric-acid esters | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1982-10-13 | — | — | EP | disclosed |