Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11300641 | 0.77 | CHRNA7 (0.67) | CHRNA7CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9493360 | 0.76 | CHRNA7 (0.61) | CHRNA7CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL3217359 | 0.76 | CHRNA7 (1.00) | CHRNA7CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL873067 | 0.74 | CHRNA7 (0.79) | CHRNA7CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9431069 | 0.73 | CHRNA7 (0.67) | CHRNA7CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL19539401 | 0.72 | CHRNA7 (0.61) | CHRNA7CHRM2CHRM4CHRM5CHRM1 | |
| Hydrochloric Acid SCHEMBL8686664 | 0.72 | CHRNA7 (0.77) | CHRNA7CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL23763949 | 0.71 | CHRNA7 (0.64) | CHRNA7CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL15176766 | 0.71 | MEN1 (0.43) | CHRNA7CHRM2CHRM1CHRM3ALDH1A1 | |
| SCHEMBL13576479 | 0.71 | LMNA (0.63) | CHRM2CHRM4CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4292190-A | ANTIFREEZES FOR COOLING SYSTEMS OF INTERNAL COMBUSTION ENGINES | BASF WYANDOTTE CORPORATION (US) | 1981-09-29 | — | — | US | disclosed |