Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.44 |
| ▸ | SRR | Q9GZT4 | 4/20 | 0.71 |
| ▸ | PSAT1 | Q9Y617 | 2/20 | 0.68 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.47 |
| ▸ | PPARA | Q07869 | 10/20 | 0.46 |
| ▸ | PPARG | P37231 | 10/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11298237 | 0.98 | SRR (0.73) | SRRPSAT1SLC7A5TAAR1PPARA | |
| Aminooxyphenylpropionate SCHEMBL1357763 | 0.85 | SRR (0.96) | SRRPSAT1SLC7A5PPARAPPARG | |
| Aminooxyphenylpropionate SCHEMBL1401589 | 0.83 | SRR (1.00) | SRRPSAT1SLC7A5PPARAPPARG | |
| Aminooxyphenylpropionate SCHEMBL6513696 | 0.83 | SRR (1.00) | SRRPSAT1SLC7A5PPARAPPARG | |
| Aminooxyphenylpropionate SCHEMBL1520985 | 0.83 | SRR (1.00) | SRRPSAT1SLC7A5PPARAPPARG | |
| SCHEMBL15446294 | 0.82 | SRR (0.71) | SRRPSAT1PPARAPPARG | |
| SCHEMBL15446243 | 0.82 | SRR (0.71) | SRRPSAT1PPARAPPARG | |
| Methylamine SCHEMBL5607639 | 0.81 | SLC7A5 (0.56) | SRRPSAT1SLC7A5TAAR1PPARA | |
| SCHEMBL15446238 | 0.81 | SRR (1.00) | SRRPSAT1PPARAPPARG | |
| SCHEMBL4451311 | 0.80 | PPARA (0.56) | SRRPSAT1SLC7A5PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0008494-B1 | METHOD OF IMPROVING OR MAINTAINING DIGESTIBILITY OF FODDER CROPS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-12-22 | — | — | EP | disclosed |
| US-4304592-A | Method of improving or maintaining digestibility of fodder crops | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-12-08 | — | — | US | disclosed |
| EP-0008494-A1 | Method of improving or maintaining digestibility of fodder crops | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1980-03-05 | — | — | EP | disclosed |