Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Aminooxyphenylpropionate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRR | Q9GZT4 | 4/20 | 0.96 |
| ▸ | PSAT1 | Q9Y617 | 2/20 | 0.77 |
| ▸ | PPARG | P37231 | 14/20 | 0.56 |
| ▸ | PPARA | Q07869 | 12/20 | 0.56 |
| ▸ | ALPI | P09923 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | XIAP | P98170 | 1/20 | 0.55 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.55 |
| ▸ | ACE | P12821 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aminooxyphenylpropionate SCHEMBL1520985 | 0.98 | SRR (1.00) | SRRPSAT1PPARGPPARAALPI | |
| Aminooxyphenylpropionate SCHEMBL6513696 | 0.98 | SRR (1.00) | SRRPSAT1PPARGPPARAALPI | |
| Aminooxyphenylpropionate SCHEMBL1401589 | 0.98 | SRR (1.00) | SRRPSAT1PPARGPPARAALPI | |
| SCHEMBL15446238 | 0.87 | SRR (1.00) | SRRPSAT1PPARGPPARA | |
| Bromide SCHEMBL11297122 | 0.85 | SRR (0.71) | SRRPSAT1PPARGPPARASLC7A5 | |
| SCHEMBL15446229 | 0.84 | SRR (0.75) | SRRPSAT1PPARGPPARA | |
| SCHEMBL288435 | 0.84 | PPARA (0.74) | SRRPSAT1PPARGPPARA | |
| SCHEMBL11298237 | 0.83 | SRR (0.73) | SRRPSAT1PPARGPPARASLC7A5 | |
| SCHEMBL15446294 | 0.81 | SRR (0.71) | SRRPSAT1PPARGPPARA | |
| SCHEMBL15446243 | 0.81 | SRR (0.71) | SRRPSAT1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110280803-A1 | RADIOIODINATION METHOD | GE HEALTHCARE UK LIMITED (GB) | 2011-11-17 | — | — | US | disclosed |
| EP-2382185-A1 | RADIOIODINATION METHOD | GE Healthcare Limited (GB) | 2011-11-02 | — | — | EP | disclosed |
| WO-2010086398-A1 | RADIOIODINATION METHOD | GE HEALTHCARE LIMITED (GB) | 2010-08-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110280803-A1 | RADIOIODINATION METHOD | TPO, SSTR5, DAO | SRR 2260/4885PSAT1 1824/4885PPARG 2555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.