SCHEMBL1129724

SCHEMBL1129724

CCCCc1ccc(N=Cc2ccc(CC)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 3/20 0.55
CYP3A4 P08684 2/20 0.55
CYP2D6 P10635 2/20 0.55
GRIN2D O15399 1/20 0.51
GRIN3B O60391 1/20 0.51
GRIN1 Q05586 1/20 0.51
GRIN2A Q12879 1/20 0.51
GRIN2B Q13224 1/20 0.51
GRIN2C Q14957 1/20 0.51
GRIN3A Q8TCU5 1/20 0.51
ALDH1A1 P00352 3/20 0.43
HSD17B10 Q99714 2/20 0.43
THRB P10828 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
KDM4E B2RXH2 1/20 0.43
MEN1 O00255 1/20 0.43
TP53 P04637 1/20 0.43
MAPT P10636 1/20 0.43
ALOX15 P16050 1/20 0.43
MAPK1 P28482 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1129722 1.00 CYP2C9 (0.55) CYP2C9CYP3A4CYP2D6GRIN2DGRIN3B
SCHEMBL11524101 0.95 CYP3A4 (0.60) CYP2C9CYP3A4CYP2D6GRIN2DGRIN3B
SCHEMBL3620867 0.95 CYP3A4 (0.60) CYP2C9CYP3A4CYP2D6GRIN2DGRIN3B
SCHEMBL6635785 0.95 CYP3A4 (0.60) CYP2C9CYP3A4CYP2D6GRIN2DGRIN3B
SCHEMBL1878786 0.94 CYP3A4 (0.57) CYP2C9CYP3A4CYP2D6GRIN2DGRIN3B
SCHEMBL10346503 0.92 CYP3A4 (0.58) CYP2C9CYP3A4CYP2D6GRIN2DGRIN3B
SCHEMBL12416611 0.92 CYP3A4 (0.58) CYP2C9CYP3A4CYP2D6GRIN2DGRIN3B
SCHEMBL5665735 0.89 CYP3A4 (0.54) CYP2C9CYP3A4CYP2D6GRIN2DGRIN3B
SCHEMBL5665730 0.89 CYP3A4 (0.54) CYP2C9CYP3A4CYP2D6GRIN2DGRIN3B
SCHEMBL12416633 0.88 CYP3A4 (0.62) CYP2C9CYP3A4CYP2D6GRIN2DGRIN3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8158135-B2 Imine based liquid crystals for the controlled release of bioactive materials FIRMENICH SA (CH) 2012-04-17 US disclosed
EP-2010231-B1 IMINE BASED LIQUID CRYSTALS FOR THE CONTROLLED RELEASE OF BIOACTIVE MATERIALS FIRMENICH & CIE (CH) 2011-02-16 EP disclosed
US-20090306196-A1 IMINE BASED LIQUID CRYSTALS FOR THE CONTROLLED RELEASE OF BIOACTIVE MATERIALS FIRMENICH SA (CH) 2009-12-10 US disclosed
EP-2010231-A2 IMINE BASED LIQUID CRYSTALS FOR THE CONTROLLED RELEASE OF BIOACTIVE MATERIALS Firmenich S.A. (CH) 2009-01-07 EP disclosed
WO-2007113711-A2 IMINE BASED LIQUID CRYSTALS FOR THE CONTROLLED RELEASE OF BIOACTIVE MATERIALS FIRMENICH SA (CH) 2007-10-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090306196-A1 IMINE BASED LIQUID CRYSTALS FOR THE CONTROLLED RELEASE OF BIOACTIVE MATERIALS BCHE, ACHE, LIPE CYP2C9 345/4885CYP3A4 1225/4885CYP2D6 2375/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.