Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 7/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL677566 | 0.72 | ALDH1A1 (0.45) | ALDH1A1KDM4EMAPTKMT2ATSHR | |
| SCHEMBL11297263 | 0.72 | KEAP1 (0.42) | KEAP1ESR1ESR2ALDH1A1TSHR | |
| SCHEMBL30374559 | 0.71 | ESR1 (0.53) | KEAP1ESR1ESR2ALDH1A1KDM4E | |
| SCHEMBL13656366 | 0.71 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPTKMT2ATSHR | |
| SCHEMBL11487730 | 0.69 | ALDH1A1 (0.42) | ALDH1A1KDM4EMAPTKMT2ATSHR | |
| SCHEMBL11437771 | 0.69 | ALDH1A1 (0.52) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL5690395 | 0.69 | ALDH1A1 (0.42) | ALDH1A1KDM4EMAPTKMT2ATSHR | |
| SCHEMBL28009450 | 0.67 | ALDH1A1 (0.47) | ALDH1A1MEN1MAPTKMT2ATSHR | |
| SCHEMBL7741024 | 0.67 | ALDH1A1 (0.47) | ALDH1A1MEN1MAPTKMT2ATSHR | |
| SCHEMBL11778379 | 0.67 | ALDH1A1 (0.39) | ALDH1A1KDM4EMAPTTSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4321343-A | Polyisobutylene/phenol polymers treated with diisocyanates and poly(oxyalkylene)polyols | W. R. GRACE & CO. (US) | 1982-03-23 | — | — | US | disclosed |
| US-4107144-A | Phenolic antioxidants with polymer tails | CANADIAN PATENTS AND DEVELOPMENT LIMITED (CA) | 1978-08-15 | — | — | US | disclosed |