Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 2/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9787517 | 0.92 | LMNA (0.35) | POLBLMNABRD4NEU3 | |
| SCHEMBL9787542 | 0.88 | HDAC8 (0.37) | LMNAKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL9239081 | 0.86 | LMNA (0.49) | LMNAKDM4EMEN1ALDH1A1HPGD | |
| SCHEMBL11300876 | 0.86 | KDM4E (0.35) | POLBLMNAKDM4EALDH1A1HPGD | |
| SCHEMBL9787518 | 0.84 | LMNA (0.30) | LMNA | |
| SCHEMBL9542743 | 0.83 | LMNA (0.38) | LMNACYP2C19HIF1A | |
| SCHEMBL9318772 | 0.82 | TP53 (0.36) | POLBTSHREGFRPLAUMKNK2 | |
| SCHEMBL11169322 | 0.82 | KDM4E (0.36) | LMNAKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL11292715 | 0.79 | LMNA (0.36) | LMNAKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL9787545 | 0.79 | LMNA (0.36) | LMNAKDM4EMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4328202-A | X-RAY CONTRAST AGENT | SCHERING, A.G. (DE) | 1982-05-04 | — | — | US | disclosed |