Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 2/20 | 0.35 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.35 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | PLK4 | O00444 | 1/20 | 0.35 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | INSR | P06213 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | ROS1 | P08922 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9000039 | 0.89 | LMNA (0.58) | LMNASMN1; SMN2FLT3KDRCSNK2A1 | |
| SCHEMBL9564018 | 0.86 | LMNA (0.63) | LMNASMN1; SMN2FLT3KDRCSNK2A1 | |
| SCHEMBL11297490 | 0.86 | POLB (0.34) | LMNALIMK1MKNK2MEN1CYP2C19 | |
| Iothalamic Acid SCHEMBL29746594 | 0.85 | LMNA (0.56) | LMNASMN1; SMN2MEN1KMT2AKDM4E | |
| Iothalamic Acid SCHEMBL38419 | 0.85 | LMNA (0.56) | LMNASMN1; SMN2MEN1KMT2AKDM4E | |
| Iothalamic Acid SCHEMBL9563103 | 0.83 | LMNA (0.55) | LMNASMN1; SMN2 | |
| SCHEMBL11223793 | 0.83 | LMNA (0.49) | LMNASMN1; SMN2 | |
| SCHEMBL11346904 | 0.83 | LMNA (0.49) | LMNASMN1; SMN2 | |
| SCHEMBL13360600 | 0.83 | LMNA (0.62) | LMNASMN1; SMN2FLT3KDRCSNK2A1 | |
| Iothalamic Acid SCHEMBL159919 | 0.82 | LMNA (0.75) | LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0530343-B1 | WATER SOLUBLE, NON-IONIC X-RAY CONTRASTING AGENTS AND PROCESS FOR PRODUCING THE SAME | KOEHLER CHEMIE DR FRANZ (DE) | 1995-09-20 | — | — | EP | disclosed |