Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 3/20 | 0.57 |
| ▸ | PON1 | P27169 | 3/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | HSD17B3 | P37058 | 4/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | GRB2 | P62993 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26158983 | 0.80 | PON1 (0.45) | MCL1PON1DYRK1APIM1KDM4E | |
| SCHEMBL5969658 | 0.80 | KMT2A (0.59) | MCL1PON1DYRK1AKDM4EMAPK1 | |
| SCHEMBL30185458 | 0.80 | HSD17B3 (0.73) | MCL1HSD17B3LCKFYNAKR1B1 | |
| SCHEMBL28294964 | 0.80 | HSD17B3 (0.73) | MCL1HSD17B3LCKFYNAKR1B1 | |
| SCHEMBL523848 | 0.80 | KDM4E (0.58) | MCL1PON1DYRK1AHSD17B3LCK | |
| SCHEMBL205186 | 0.80 | HSD17B3 (0.73) | MCL1HSD17B3LCKFYNAKR1B1 | |
| SCHEMBL1209429 | 0.77 | PON1 (0.58) | MCL1PON1DYRK1AHSD17B3KDM4E | |
| SCHEMBL29145862 | 0.77 | KDM4E (0.54) | MCL1HSD17B3PIM1AKR1B1KDM4E | |
| SCHEMBL6229629 | 0.76 | DYRK1A (0.78) | MCL1DYRK1ALCKKDM4ERAB9A | |
| SCHEMBL14669803 | 0.76 | SLC18A1 (0.70) | MCL1PON1DYRK1AHSD17B3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2666010-A1 | OPTICAL SENSOR | The City University (GB) | 2013-11-27 | — | — | EP | claimed |
| WO-2012098242-A1 | OPTICAL SENSOR | CITY UNIVERSITY (GB) | 2012-07-26 | — | — | WO | claimed |
| EP-2666010-A1 | OPTICAL SENSOR | The City University (GB) | 2013-11-27 | — | — | EP | disclosed |
| WO-2012098242-A1 | OPTICAL SENSOR | CITY UNIVERSITY (GB) | 2012-07-26 | — | — | WO | disclosed |