Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PON1 | P27169 | 3/20 | 0.58 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.58 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.57 |
| ▸ | NQO1 | P15559 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5459900 | 0.83 | CA12 (0.61) | MCL1NQO1CA12CA1CA9 | |
| SCHEMBL30486066 | 0.83 | CA12 (0.61) | MCL1NQO1CA12CA1CA9 | |
| SCHEMBL8372531 | 0.83 | HSD17B3 (0.62) | NQO1CA12CA1CA9CYP19A1 | |
| SCHEMBL18138409 | 0.83 | NQO1 (0.58) | NQO1CA12CA1CA9CYP19A1 | |
| SCHEMBL4211791 | 0.81 | NQO1 (0.61) | NQO1CA12CA1CA9CYP19A1 | |
| SCHEMBL294208 | 0.81 | NQO1 (0.56) | NQO1CA12CA1CA9CYP19A1 | |
| SCHEMBL637265 | 0.81 | NQO1 (0.56) | NQO1CA12CA1CA9CYP19A1 | |
| SCHEMBL28217721 | 0.81 | NQO1 (0.56) | NQO1CA12CA1CA9CYP19A1 | |
| B-D-Galactose SCHEMBL5884183 | 0.80 | MCL1 (0.43) | PON1DYRK1AMCL1CA12CA1 | |
| SCHEMBL14735837 | 0.80 | NQO1 (0.55) | NQO1CA12CA1CA9CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160334393-A1 | Use of Novel Coumarins as Glutathione and Thiol Labels | Life Technologies Corporation | 2016-11-17 | — | — | US | disclosed |
| WO-2015199141-A1 | COUMALIN-BASED CONDENSED RING COMPOUND EXHIBITING LUMINESCENCE/SEMICONDUCTOR PROPERTIES, AND METHOD FOR MANUFACTURING SAME | 国立大学法人 群馬大学 | 2015-12-30 | — | — | WO | disclosed |
| US-20150219634-A1 | Use of Novel Coumarins as Glutathione and Thiol Labels | LIFE TECHNOLOGIES CORP (US) | 2015-08-06 | — | — | US | disclosed |
| US-8981100-B2 | Use of novel coumarins as glutathione and thiol labels | Life Technologies Corporation (US) | 2015-03-17 | — | — | US | disclosed |
| US-20120302566-A1 | INDANYLOXYDIHYDROBENZOFURANYLACETIC ACIDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-11-29 | — | — | US | disclosed |
| US-20110045503-A1 | The Use of Novel Coumarins as Glutathione and Thiol Labels | Life Technologies Corporation (US) | 2011-02-24 | — | — | US | disclosed |
| US-7811332-B2 | does not require exogenous cells; surgical repair of bladder and urethra defects; implanting shaped fibrous, synthetic biodegradable poly(lactic acid-glycolic acid)matrix (interstitial spacing 100-300 mu) to form scaffolding; covering with omentum or Gerota's fascia to render impermeable to urine | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2010-10-12 | — | — | US | disclosed |
| WO-2009018112-A2 | THE USE OF NOVEL COUMARINS AS GLUTATHIONE AND THIOL LABELS | INVITROGEN CORPORATION (US) | 2009-02-05 | — | — | WO | disclosed |
| US-20060002972-A1 | Reconstruction of urological structures with polymeric matrices | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2006-01-05 | — | — | US | disclosed |
| US-20030120352-A1 | Reconstruction of urologic structures with polymeric matrices | ATALA ANTHONY (US) | 2003-06-26 | — | — | US | disclosed |
| US-20020055786-A1 | RECONSTRUCTION OF UROLOGICAL STRUCTURES WITH POLYMERIC MATRICES | ATALA ANTHONY (US) | 2002-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150219634-A1 | Use of Novel Coumarins as Glutathione and Thiol Labels | GSTP1, GSTK1, GSTA1 | PON1 1580/4885DYRK1A 4535/4885MCL1 572/4885 |
| US-20160334393-A1 | Use of Novel Coumarins as Glutathione and Thiol Labels | GSTP1, GSTK1, GSTA1 | PON1 1580/4885DYRK1A 4535/4885MCL1 572/4885 |
| US-20110045503-A1 | The Use of Novel Coumarins as Glutathione and Thiol Labels | GSTP1, GSTK1, GSTA1 | PON1 1429/4885DYRK1A 4538/4885MCL1 806/4885 |
| US-20120302566-A1 | INDANYLOXYDIHYDROBENZOFURANYLACETIC ACIDS | GPR119, INSR, GPR52 | PON1 1974/4885DYRK1A 3269/4885MCL1 4741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.