Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA6 | P23280 | 3/20 | 0.39 |
| ▸ | CA7 | P43166 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.39 |
| ▸ | CA3 | P07451 | 3/20 | 0.39 |
| ▸ | CA5A | P35218 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2448920 | 0.94 | CA5B (0.44) | TDP1CA5BCA12CA6CA7 | |
| SCHEMBL6135318 | 0.94 | CA5B (0.44) | TDP1CA5BCA12CA6CA7 | |
| SCHEMBL11303971 | 0.93 | PAOX (0.46) | TDP1CA5BCA12CA6CA7 | |
| SCHEMBL9061857 | 0.89 | TDP1 (0.55) | TDP1CA5BCA12CA6CA7 | |
| Trientine SCHEMBL732582 | 0.89 | TDP1 (0.55) | TDP1CA5BCA12CA6CA7 | |
| Trientine SCHEMBL3252613 | 0.89 | TDP1 (0.55) | TDP1CA5BCA12CA6CA7 | |
| Trientine SCHEMBL3254942 | 0.89 | TDP1 (0.55) | TDP1CA5BCA12CA6CA7 | |
| SCHEMBL15271465 | 0.87 | PAOX (0.50) | TDP1CA5BCA12CA6CA7 | |
| SCHEMBL1736356 | 0.87 | TDP1 (0.57) | TDP1CA5BCA12CA6CA7 | |
| SCHEMBL167512 | 0.87 | TDP1 (0.57) | TDP1CA5BCA12CA6CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0032905-A4 | CONTACT LENSES WITH POLYMER BOUND ASEPTICIZING AGENTS. | FOLEY WILLIAM M JUN | 1981-08-27 | — | — | EP | disclosed |
| EP-0032905-A1 | CONTACT LENSES WITH POLYMER BOUND ASEPTICIZING AGENTS | FOLEY, Jr., William M. (US) | 1981-08-05 | — | — | EP | disclosed |
| WO-1980002840-A1 | CONTACT LENSES WITH POLYMER BOUND ASEPTICIZING AGENTS | FOLEY W | 1980-12-24 | — | — | WO | disclosed |