Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA6 | P23280 | 3/20 | 0.44 |
| ▸ | CA7 | P43166 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | CA3 | P07451 | 3/20 | 0.44 |
| ▸ | CA5A | P35218 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2448920 | 1.00 | CA5B (0.44) | CA5BCA12CA6CA7CA9 | |
| SCHEMBL11298147 | 0.94 | TDP1 (0.43) | CA5BCA12CA6CA7CA9 | |
| SCHEMBL15271465 | 0.92 | PAOX (0.50) | CA5BCA12CA6CA7CA9 | |
| SCHEMBL16267884 | 0.89 | TGFBR1 (0.38) | CA5BTDP1CA3CA5AALDH1A1 | |
| SCHEMBL11303971 | 0.88 | PAOX (0.46) | CA5BCA12CA6CA7CA9 | |
| SCHEMBL50166 | 0.87 | — | — | |
| Ammonia Solution, Strong SCHEMBL27914279 | 0.85 | PAOX (0.39) | TDP1ALOX15ALDH1A1KDM4EPAOX | |
| Hydrochloric Acid SCHEMBL452866 | 0.85 | PAOX (0.39) | TDP1ALOX15ALDH1A1KDM4EPAOX | |
| Hydrochloric Acid SCHEMBL7770837 | 0.83 | PAOX (0.38) | TDP1ALOX15ALDH1A1KDM4EPAOX | |
| SCHEMBL28954974 | 0.83 | PAOX (0.52) | TDP1KDM4EPAOXTGFBR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1296697-A4 | THERAPEUTIC AGENTS - I | PEPLIN RESEARCH PTY LTD (AU) | 2005-02-16 | — | — | EP | claimed |
| EP-1296697-A1 | THERAPEUTIC AGENTS - I | Peplin Research Pty Ltd (AU) | 2003-04-02 | — | — | EP | claimed |
| WO-2001093884-A1 | THERAPEUTIC AGENTS - I | PEPLIN RESEARCH PTY. LTD. (AU) | 2001-12-13 | — | — | WO | claimed |