SCHEMBL11298243

SCHEMBL11298243

CCC[C@H](NC(=O)[C@@H](NC(=O)CN(C)C(=O)OCc1ccccc1)C(C)C)C(=O)N[C@@H](C)P(=O)(O)O

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CTSK P43235 3/20 0.42
CASP1 P29466 2/20 0.39
CASP3 P42574 2/20 0.39
CASP9 P55211 2/20 0.39
CASP7 P55210 1/20 0.39
ECE1 P42892 4/20 0.39
MME P08473 2/20 0.39
CTSB P07858 2/20 0.38
CACNA1H O95180 1/20 0.38
CASP4 P49662 1/20 0.37
CASP5 P51878 1/20 0.37
CASP6 P55212 1/20 0.37
CASP8 Q14790 1/20 0.37
CASP10 Q92851 1/20 0.37
LNPEP Q9UIQ6 2/20 0.37
ERAP2 Q6P179 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11304755 0.99 CTSK (0.42) CTSKCASP1CASP3CASP9CASP7
SCHEMBL11305172 0.94 CTSK (0.46) CTSKECE1MMECACNA1H
SCHEMBL11299562 0.91 REN (0.44) CTSKECE1MMECACNA1H
SCHEMBL11304064 0.89 CTSK (0.43) CTSKCACNA1H
SCHEMBL11303050 0.88 CTSK (0.42) CTSKCACNA1H
SCHEMBL11308607 0.87 CTSK (0.43) CTSKCACNA1H
SCHEMBL11308831 0.86 CTSK (0.42) CTSKCASP1CASP3CASP9CASP7
SCHEMBL11299994 0.85 CTSK (0.55) CTSKCASP1CASP3CASP9CASP7
SCHEMBL11301057 0.84 CTSK (0.54) CTSKCASP1CASP3CASP9CASP7
SCHEMBL11298776 0.84 CTSL (0.43) CTSKCACNA1H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4250085-A PHOSPHONATE-CONTAINING OLIGOPEPTIDES, BACTERICIDES HOFFMANN-LA ROCHE INC. (US) 1981-02-10 US disclosed