Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | CCR6 | P51684 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | PTGIR | P43119 | 1/20 | 0.44 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL801192 | 0.90 | CCR6 (0.54) | ALDH1A1CCR6PAX8LMNAMAPK1 | |
| SCHEMBL16665613 | 0.90 | ALDH1A1 (0.58) | ALDH1A1CCR6PAX8PTGDR2LMNA | |
| SCHEMBL13049197 | 0.88 | CCR6 (0.50) | ALDH1A1CCR6PAX8PTGDR2LMNA | |
| SCHEMBL11307171 | 0.86 | ALDH1A1 (0.47) | ALDH1A1CCR6PAX8PTGDR2LMNA | |
| SCHEMBL11605776 | 0.86 | SLC6A2 (0.50) | ALDH1A1CCR6PAX8PTGDR2LMNA | |
| SCHEMBL4692471 | 0.86 | ALDH1A1 (0.54) | ALDH1A1CCR6PAX8LMNAMAPK1 | |
| Hydrochloric Acid SCHEMBL23354638 | 0.86 | CCR6 (0.46) | ALDH1A1CCR6PAX8PTGDR2LMNA | |
| SCHEMBL13687190 | 0.85 | LMNA (0.62) | ALDH1A1CCR6PAX8PTGDR2LMNA | |
| SCHEMBL2787581 | 0.85 | CCR6 (0.50) | ALDH1A1CCR6PAX8LMNAMAPK1 | |
| SCHEMBL24821066 | 0.85 | CCR6 (0.54) | ALDH1A1CCR6PAX8LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12054485-B2 | Substituted imidazoquinolines | BioNTech SE (DE) | 2024-08-06 | — | — | US | disclosed |
| EP-4403225-A2 | SUBSTITUTED IMIDAZOQUINOLINES | BioNTech SE (DE) | 2024-07-24 | — | — | EP | disclosed |
| US-11987569-B2 | Substituted imidazoquinolines as agonists of TLR7 | BioNTech SE (DE) | 2024-05-21 | — | — | US | disclosed |
| EP-3679038-B1 | SUBSTITUTED IMIDAZOQUINOLINES | BioNTech SE (DE) | 2024-04-03 | — | — | EP | disclosed |
| CN-111132969-B | Substituted imidazoquinolines as TLR7 agonists | 生物技术公司 | 2024-01-30 | — | — | CN | disclosed |
| EP-4098652-A1 | SUBSTITUTED IMIDAZOQUINOLINES AS AGONISTS OF TLR7 | BioNTech SE (DE) | 2022-12-07 | — | — | EP | disclosed |
| US-20220242845-A1 | SUBSTITUTED IMIDAZOQUINOLINES AS AGONISTS OF TLR7 | BioNTech SE (DE) | 2022-08-04 | — | — | US | disclosed |
| US-20220227756-A1 | SUBSTITUTED IMIDAZOQUINOLINES | BioNTech SE (DE) | 2022-07-21 | — | — | US | disclosed |
| EP-3679025-B1 | SUBSTITUTED IMIDAZOQUINOLINES AS AGONISTS OF TLR7 | BioNTech SE (DE) | 2022-05-04 | — | — | EP | disclosed |
| US-11279684-B2 | Substituted imidazoquinolines as agonists of TLR7 | Bointech SE | 2022-03-22 | — | — | US | disclosed |
| US-11267813-B2 | Substituted imidazoquinolines | BioNTech SE | 2022-03-08 | — | — | US | disclosed |
| CN-111132969-A | Substituted imidazoquinolines as TLR7 agonists | 生物技术公司 | 2020-05-08 | — | — | CN | disclosed |
| CN-111094287-A | Substituted imidazoquinolines | 生物技术公司 | 2020-05-01 | — | — | CN | disclosed |
| US-4250085-A | PHOSPHONATE-CONTAINING OLIGOPEPTIDES, BACTERICIDES | HOFFMANN-LA ROCHE INC. (US) | 1981-02-10 | — | — | US | disclosed |
| EP-0002822-A1 | Phosphorus containing peptide derivatives, their production, intermediates for their production and pharmaceutical compositions containing them | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1979-07-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12054485-B2 | Substituted imidazoquinolines | TLR7, TLR3, TLR1 | ALDH1A1 2446/4885CCR6 259/4885PAX8 3780/4885 |
| US-11279684-B2 | Substituted imidazoquinolines as agonists of TLR7 | TLR7, TLR3, TLR1 | ALDH1A1 2535/4885CCR6 432/4885PAX8 3421/4885 |
| US-11987569-B2 | Substituted imidazoquinolines as agonists of TLR7 | TLR7, TLR3, TLR1 | ALDH1A1 2535/4885CCR6 432/4885PAX8 3421/4885 |
| US-11267813-B2 | Substituted imidazoquinolines | TLR7, TLR3, TLR1 | ALDH1A1 2446/4885CCR6 259/4885PAX8 3780/4885 |
| US-20220227756-A1 | SUBSTITUTED IMIDAZOQUINOLINES | TLR7, TLR3, TLR1 | ALDH1A1 2446/4885CCR6 259/4885PAX8 3780/4885 |
| US-20220242845-A1 | SUBSTITUTED IMIDAZOQUINOLINES AS AGONISTS OF TLR7 | TLR7, TLR3, TLR1 | ALDH1A1 2535/4885CCR6 432/4885PAX8 3421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.