Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.46 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HSD17B3 | P37058 | 6/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11292052 | 0.98 | PLA2G2A (0.49) | HTTPLA2G2APLA2G5FFAR1MEN1 | |
| Hydrochloric Acid SCHEMBL11293609 | 0.97 | PLA2G2A (0.48) | HTTPLA2G2APLA2G5FFAR1MEN1 | |
| SCHEMBL11288827 | 0.95 | CYP3A4 (0.45) | HTTPLA2G2APLA2G5FFAR1MEN1 | |
| SCHEMBL11285848 | 0.89 | ALDH1A1 (0.47) | HTTCYP3A4HSD17B3NOS2ALDH1A1 | |
| SCHEMBL10355740 | 0.84 | AKR1C2 (0.51) | HTTPLA2G2APLA2G5FFAR1MEN1 | |
| SCHEMBL15535075 | 0.83 | PLA2G2A (0.51) | HTTPLA2G2APLA2G5FFAR1MEN1 | |
| SCHEMBL10355851 | 0.83 | PLA2G2A (0.51) | HTTPLA2G2APLA2G5FFAR1MEN1 | |
| SCHEMBL11288946 | 0.83 | CYP1A2 (0.41) | MEN1KMT2ACYP3A4NOS2ALDH1A1 | |
| SCHEMBL11293169 | 0.82 | TSHR (0.43) | CYP3A4NOS2CA2ALDH1A1MAPT | |
| SCHEMBL11296661 | 0.82 | CYP3A4 (0.50) | MEN1KMT2ACYP3A4NOS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0065874-A1 | 2-Aminophenol derivatives, methods for their preparation and composition containing the same | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-12-01 | — | — | EP | disclosed |