Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 3/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | NOS2 | P35228 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11288073 | 0.93 | CYP3A4 (0.41) | CYP1A2CYP3A4NPC1LMNAPOLB | |
| SCHEMBL11293169 | 0.86 | TSHR (0.43) | CYP3A4TSHRHPGDKDM4EALDH1A1 | |
| SCHEMBL11306000 | 0.86 | HPGD (0.43) | CYP3A4LMNATSHRHPGDKDM4E | |
| SCHEMBL11288827 | 0.84 | CYP3A4 (0.45) | CYP3A4TSHRHPGDKDM4EALDH1A1 | |
| SCHEMBL11295366 | 0.84 | CYP1A2 (0.41) | CYP1A2CYP3A4NPC1LMNATSHR | |
| SCHEMBL11298360 | 0.83 | HTT (0.48) | CYP3A4ALDH1A1NOS2MEN1KMT2A | |
| SCHEMBL11292052 | 0.82 | PLA2G2A (0.49) | CYP3A4ALDH1A1NOS2MEN1KMT2A | |
| SCHEMBL11293235 | 0.82 | CYP1A2 (0.40) | CYP1A2NPC1POLBRAB9ATNF | |
| SCHEMBL11285848 | 0.81 | ALDH1A1 (0.47) | CYP3A4LMNATSHRHPGDKDM4E | |
| Hydrochloric Acid SCHEMBL11293609 | 0.81 | PLA2G2A (0.48) | CYP3A4ALDH1A1NOS2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0065874-A1 | 2-Aminophenol derivatives, methods for their preparation and composition containing the same | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-12-01 | — | — | EP | disclosed |