Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7684345 | 0.76 | ALDH1A1 (0.31) | ALDH1A1TDP1 | |
| SCHEMBL10788942 | 0.75 | — | — | |
| SCHEMBL12039453 | 0.70 | — | — | |
| SCHEMBL10313767 | 0.70 | TSHR (0.34) | TSHRALDH1A1TDP1ACHEHSD17B10 | |
| SCHEMBL9743198 | 0.66 | — | — | |
| SCHEMBL19181459 | 0.63 | EEF2K (0.43) | — | |
| SCHEMBL5842044 | 0.62 | MEN1 (0.30) | MEN1KMT2A | |
| SCHEMBL8369703 | 0.61 | — | — | |
| SCHEMBL15287431 | 0.61 | ACHE (0.31) | TSHRALDH1A1TDP1ACHEHSD17B10 | |
| SCHEMBL11802296 | 0.60 | LMNA (0.33) | TSHRALDH1A1TDP1ACHELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102718692-A | Preparation method of 7-bit methyl-5-bit oxygen-substituted indole compounds | SUZHOU HEJIAN MEDICAL TECHNOLOGY CO LTD | 2012-10-10 | — | — | CN | claimed |
| CN-102718692-B | Preparation method of 7-bit methyl-5-bit oxygen-substituted indole compounds | SUZHOU HEJIAN MEDICAL TECHNOLOGY CO LTD | 2014-01-08 | — | — | CN | disclosed |
| CN-102718692-B | Preparation method of 7-bit methyl-5-bit oxygen-substituted indole compounds | SUZHOU HEJIAN MEDICAL TECHNOLOGY CO LTD | 2014-01-08 | — | — | CN | disclosed |
| CN-102718692-A | Preparation method of 7-bit methyl-5-bit oxygen-substituted indole compounds | SUZHOU HEJIAN MEDICAL TECHNOLOGY CO LTD | 2012-10-10 | — | — | CN | disclosed |
| CN-102718692-A | Preparation method of 7-bit methyl-5-bit oxygen-substituted indole compounds | SUZHOU HEJIAN MEDICAL TECHNOLOGY CO LTD | 2012-10-10 | — | — | CN | disclosed |
| EP-0019744-B1 | PROCESS FOR THE PREPARATION OF 3-NITRO-4-METHYLPHENYL CHLOROFORMATE | BASF Aktiengesellschaft (DE) | 1982-12-29 | — | — | EP | disclosed |