SCHEMBL29370004

SCHEMBL29370004

CC(C)(C)c1cc(C=NCCCN=Cc2cc(C(C)(C)C)cc(C(C)(C)C)c2O)c(O)c(C(C)(C)C)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 4/20 0.49
PTGS2 P35354 4/20 0.49
SMN1; SMN2 Q16637 2/20 0.43
KDM4E B2RXH2 1/20 0.43
MEN1 O00255 1/20 0.43
USP2 O75604 1/20 0.43
ALDH1A1 P00352 1/20 0.43
LMNA P02545 1/20 0.43
KMT2A Q03164 1/20 0.43
CA12 O43570 1/20 0.40
CA2 P00918 1/20 0.40
CA9 Q16790 1/20 0.40
HTT P42858 1/20 0.40
HIF1A Q16665 5/20 0.39
NR5A2 O00482 1/20 0.39
NR5A1 Q13285 1/20 0.39
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2221207 1.00 ALOX5 (0.49) ALOX5PTGS2SMN1; SMN2KDM4EMEN1
SCHEMBL13321375 1.00 ALOX5 (0.49) ALOX5PTGS2SMN1; SMN2KDM4EMEN1
SCHEMBL2221201 1.00 ALOX5 (0.49) ALOX5PTGS2SMN1; SMN2KDM4EMEN1
SCHEMBL29535850 0.94 ALOX5 (0.51) ALOX5PTGS2SMN1; SMN2KDM4EMEN1
SCHEMBL29785796 0.94 ALOX5 (0.51) ALOX5PTGS2SMN1; SMN2KDM4EMEN1
SCHEMBL3998710 0.94 ALOX5 (0.51) ALOX5PTGS2SMN1; SMN2KDM4EMEN1
SCHEMBL3998711 0.94 ALOX5 (0.51) ALOX5PTGS2SMN1; SMN2KDM4EMEN1
SCHEMBL23644507 0.93 ALOX5 (0.46) ALOX5PTGS2SMN1; SMN2KDM4EMEN1
SCHEMBL18489625 0.93 ALOX5 (0.46) ALOX5PTGS2SMN1; SMN2KDM4EMEN1
SCHEMBL3012002 0.92 ALOX5 (0.50) ALOX5PTGS2SMN1; SMN2KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122091405-A Composite activated carbon and preparation method and application thereof 2026-05-26 CN claimed
EP-4077489-B1 POLYACRYLATE-BASED GRAFT COPOLYMER SABIC GLOBAL TECHNOLOGIES BV (NL) 2026-03-11 EP claimed
US-12479946-B2 Polyacrylate-based graft copolymer SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2025-11-25 US claimed
CN-119912332-A Preparation method of high-optical-purity (S) -indoxacarb intermediate 遵义医科大学 2025-05-02 CN claimed
WO-2025073644-A1 NON-TOXIC LATENT POLYMERIZATION CATALYSTS FOR POLYURETHANES BASED ON TIN (IV) CHELATE COMPLEXES TECH SYNT LTD (GB) 2025-04-10 WO claimed
EP-4534577-A1 NON-TOXIC LATENT POLYMERIZATION CATALYSTS FOR POLYURETHANES BASED ON TIN (IV) CHELATE COMPLEXES Tech Synt Ltd (GB) 2025-04-09 EP claimed
CN-119019285-A Synthesis method of chiral alpha, alpha-disubstituted (N-hydroxy) amino acid compound 山东第一医科大学(山东省医学科学院) 2024-11-26 CN claimed
CN-116589376-A Method for synthesizing chiral alpha- (N-hydroxy) amino acid amide under mild condition 山东大学 2023-08-15 CN claimed
CN-116462626-A Method for synthesizing carbazole N-H functionalized product based on Fe catalysis at normal temperature and normal pressure 山东大学 2023-07-21 CN claimed
CN-116171858-A Tissue culture and rapid propagation method of Mahalate iron orchid 厦门市园林植物园 2023-05-30 CN claimed
US-20230026134-A1 POLYACRYLATE-BASED GRAFT COPOLYMER SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2023-01-26 US claimed
EP-4077489-A1 POLYACRYLATE-BASED GRAFT COPOLYMER SABIC Global Technologies B.V. (NL) 2022-10-26 EP claimed
CN-115094233-A Method for efficiently utilizing full-size grade of iron selamestron 抚顺新钢铁有限责任公司 2022-09-23 CN claimed
CN-114846056-A Polyacrylate-based graft copolymers SABIC环球技术有限责任公司 2022-08-02 CN claimed
CN-122091405-A Composite activated carbon and preparation method and application thereof 2026-05-26 CN disclosed
US-12629639-B2 Spacer for a spiral wound membrane EVOVE LTD (GB) 2026-05-19 US disclosed
CN-119039215-B Dimethylenepyridine bridged amino bisphenol oxy alkali metal complex and preparation method and application thereof 华东理工大学 2026-05-15 CN disclosed
EP-3983470-A1 PROCESS FOR THE CARBONYLATION OF EPOXIDES Covestro Intellectual Property GmbH & Co. KG (DE) 2022-04-20 EP disclosed
US-11299453-B2 Compounds for use in the elimination of pluripotent stem cells UNIVERSITÄT ZU KÖLN (DE) 2022-04-12 US disclosed
US-11236197-B2 Multi-block copolymers IP2IPO INNOVATIONS LIMITED (GB) 2022-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11299453-B2 Compounds for use in the elimination of pluripotent stem cells ALPG, RARB, RARG ALOX5 3324/4885PTGS2 2537/4885SMN1; SMN2 1033/4885
US-12629639-B2 Spacer for a spiral wound membrane AQP1, AQP3, AQP4 ALOX5 4694/4885PTGS2 3126/4885SMN1; SMN2 3946/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.