Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.39 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.39 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2221207 | 1.00 | ALOX5 (0.49) | ALOX5PTGS2SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL29370004 | 1.00 | ALOX5 (0.49) | ALOX5PTGS2SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL13321375 | 1.00 | ALOX5 (0.49) | ALOX5PTGS2SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL29535850 | 0.94 | ALOX5 (0.51) | ALOX5PTGS2SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL29785796 | 0.94 | ALOX5 (0.51) | ALOX5PTGS2SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL3998710 | 0.94 | ALOX5 (0.51) | ALOX5PTGS2SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL3998711 | 0.94 | ALOX5 (0.51) | ALOX5PTGS2SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL23644507 | 0.93 | ALOX5 (0.46) | ALOX5PTGS2SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL18489625 | 0.93 | ALOX5 (0.46) | ALOX5PTGS2SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL3012002 | 0.92 | ALOX5 (0.50) | ALOX5PTGS2SMN1; SMN2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9242955-B2 | Synthesis of cyclic carbonates | UNIVERSITY OF YORK (GB) | 2016-01-26 | — | — | US | disclosed |
| US-20130030144-A1 | STAR POLYMERS HAVING CONTROLLED TACTICITY AND METHODS OF MAKING SAME | SHAVER MICHAEL P (CA) | 2013-01-31 | — | — | US | disclosed |
| EP-2146977-B1 | SYNTHESIS OF CYCLIC CARBONATES IN THE PRESENCE OF DIMERIC ALUMINIUM (SALEN) CATALYSTS | UNIV NEWCASTLE (GB) | 2012-11-14 | — | — | EP | disclosed |
| WO-2011082479-A1 | STAR POLYMERS HAVING CONTROLLED TACTICITY AND METHODS OF MAKING SAME | UNIVERSITY OF PRINCE EDWARD ISLAND (CA) | 2011-07-14 | — | — | WO | disclosed |
| US-20100130752-A1 | SYNTHESIS OF CYCLIC CARBONATES | UNIVERSITY OF NEWCASTLE UPON TYNE (GB) | 2010-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130752-A1 | SYNTHESIS OF CYCLIC CARBONATES | CA2, SCO2, CA7 | ALOX5 137/4885PTGS2 339/4885SMN1; SMN2 3674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.