Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | HTR2B | P41595 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2036589 | 1.00 | SIGMAR1 (0.47) | SIGMAR1HTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL7599981 | 1.00 | SIGMAR1 (0.47) | SIGMAR1HTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL7609590 | 1.00 | SIGMAR1 (0.47) | SIGMAR1HTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL7599978 | 1.00 | SIGMAR1 (0.47) | SIGMAR1HTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL11298526 | 0.84 | HTR2A (0.51) | HTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL8527042 | 0.84 | ESR2 (0.40) | — | |
| SCHEMBL11291691 | 0.84 | HTR2A (0.53) | HTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL1388099 | 0.84 | SIGMAR1 (0.55) | SIGMAR1HTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL11548037 | 0.81 | — | — | |
| SCHEMBL11885856 | 0.80 | DRD2 (0.51) | HTR2AHTR2CHTR2BHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1261677-A1 | THERMAL FLUID BLENDS CONTAINING 1, 2, 3, 4-TETRAHYDRO(1-PHENYLETHYL)NAPHTHALENE | THE DOW CHEMICAL COMPANY (US) | 2002-12-04 | — | — | EP | disclosed |
| WO-2001059029-A1 | THERMAL FLUID BLENDS CONTAINING 1,2,3,4-TETRAHYDRO(1-PHENYLETHYL)NAPHTHALENE | DOW GLOBAL TECHNOLOGIES INC. (US) | 2001-08-16 | — | — | WO | disclosed |