Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 6/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.31 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.31 |
| ▸ | KDM4A | O75164 | 1/20 | 0.31 |
| ▸ | KDM4B | O94953 | 1/20 | 0.31 |
| ▸ | KDM5C | P41229 | 1/20 | 0.31 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3825889 | 0.80 | KDM4E (0.41) | PARP1ABL1RIN1GSK3BCHEK1 | |
| SCHEMBL1129988 | 0.69 | GRM5 (0.41) | PARP1ABL1RIN1ADORA1IP6K1 | |
| SCHEMBL83683 | 0.67 | KDM4E (0.52) | SMN1; SMN2ABL1RIN1CYP1A2IP6K1 | |
| SCHEMBL10271336 | 0.67 | KDM4E (0.55) | SMN1; SMN2CYP1A2CYP2C9ADORA1 | |
| SCHEMBL27017989 | 0.67 | KMO (0.41) | FLT3 | |
| SCHEMBL22010374 | 0.67 | KMO (0.44) | SMN1; SMN2 | |
| SCHEMBL30892721 | 0.66 | ADORA2A (0.39) | SMN1; SMN2CYP1A2CYP2C9ADORA1 | |
| SCHEMBL13779843 | 0.65 | — | — | |
| SCHEMBL503382 | 0.65 | — | — | |
| SCHEMBL4709224 | 0.65 | GSK3B (0.50) | SMN1; SMN2PDE3BPDE3ACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2033963-B1 | Substituted 2-(diaza-bicyclo-alkyl)-pyrimidone derivatives | SANOFI AVENTIS (FR) | 2011-02-16 | — | — | EP | claimed |
| EP-2033963-A1 | Substituted 2-(diaza-bicyclo-alkyl)-pyrimidone derivatives | Sanofi-Aventis (FR) | 2009-03-11 | — | — | EP | claimed |