Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | LSS | P48449 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GCK | P35557 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7352591 | 0.84 | DRD2 (0.71) | DRD2DRD3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13416032 | 0.84 | DRD2 (0.71) | DRD2DRD3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13416035 | 0.83 | ALDH1A1 (0.53) | DRD2DRD3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11297975 | 0.81 | DRD2 (0.76) | DRD2DRD3KDM2B | |
| SCHEMBL11263083 | 0.81 | DRD2 (0.59) | DRD2HTR2ADRD3KDM2B | |
| SCHEMBL21341950 | 0.80 | HTR2A (0.48) | DRD2HTR2ADRD3KCNH2ALDH1A1 | |
| SCHEMBL20789976 | 0.78 | ALDH1A1 (0.50) | DRD2ALDH1A1 | |
| SCHEMBL17514730 | 0.78 | ALDH1A1 (0.50) | DRD2ALDH1A1LMNA | |
| SCHEMBL15649846 | 0.77 | DRD2 (0.55) | DRD2HTR2ADRD3KCNH2KDM2B | |
| SCHEMBL7723674 | 0.76 | ALDH1A1 (0.48) | DRD2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0062018-A1 | Novel phenyl-piperidines | Aktiebolaget Hässle (SE) | 1982-10-06 | — | — | EP | disclosed |