Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.48 |
| ▸ | FPR1 | P21462 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21341964 | 0.83 | KDM2B (0.48) | FPR1DRD2DRD3 | |
| SCHEMBL21342024 | 0.83 | KDM2B (0.48) | HTR2AFPR1FPR2CCNT1CDK9 | |
| SCHEMBL21342317 | 0.82 | DRD2 (0.46) | FPR1FPR2CCNT1CDK9DRD2 | |
| SCHEMBL21342427 | 0.82 | FPR1 (0.48) | FPR1FPR2CCNT1CDK9DRD2 | |
| SCHEMBL21342436 | 0.80 | DRD2 (0.44) | HTR2AFPR1FPR2DRD2DRD3 | |
| SCHEMBL11298951 | 0.80 | DRD2 (0.51) | HTR2ADRD2KCNH2ALDH1A1DRD3 | |
| SCHEMBL21341956 | 0.77 | DRD2 (0.39) | HTR2AFPR1FPR2DRD2ALDH1A1 | |
| SCHEMBL21341995 | 0.75 | PDE4B (0.46) | ALDH1A1 | |
| SCHEMBL20976569 | 0.73 | PIK3CD (0.47) | HTR2AHTR2C | |
| SCHEMBL13416035 | 0.73 | ALDH1A1 (0.53) | DRD2KCNH2ALDH1A1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019170904-A1 | PIPERIDINES OR PIPERIDONES SUBSTITUTED WITH UREA AND PHENYL | Grünenthal GmbH (DE) | 2019-09-12 | — | — | WO | disclosed |