Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2322710 | 0.84 | CES1 (0.52) | L3MBTL1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL6309158 | 0.79 | L3MBTL1 (0.52) | L3MBTL1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL2448732 | 0.79 | L3MBTL1 (0.52) | L3MBTL1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL4066362 | 0.79 | L3MBTL1 (0.52) | L3MBTL1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL571046 | 0.79 | L3MBTL1 (0.85) | L3MBTL1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL9147717 | 0.75 | ALDH1A1 (0.48) | L3MBTL1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL5680205 | 0.75 | L3MBTL1 (0.57) | L3MBTL1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL8406795 | 0.74 | L3MBTL1 (0.66) | L3MBTL1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL7767316 | 0.74 | L3MBTL1 (0.66) | L3MBTL1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL19936252 | 0.72 | L3MBTL1 (0.45) | L3MBTL1MAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2282753-A1 | ASSAY FOR PATHOGENIC CONFORMERS | Novartis AG (CH) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009134942-A1 | ASSAY FOR PATHOGENIC CONFORMERS | NOVARTIS AG. (CH) | 2009-11-05 | — | — | WO | disclosed |