Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.70 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.70 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.46 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | UNG | P13051 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzaldehyde SCHEMBL27520789 | 0.90 | ALDH1A1 (0.78) | ALDH1A1CYP2A6ALDH3A1ALDH1A3MAPK1 | |
| Benzaldehyde SCHEMBL27780817 | 0.87 | ALDH1A1 (0.74) | ALDH1A1CYP2A6ALDH3A1ALDH1A3MAPK1 | |
| Benzaldehyde SCHEMBL3088932 | 0.87 | ALDH1A1 (0.74) | ALDH1A1CYP2A6ALDH3A1ALDH1A3MAPK1 | |
| Benzaldehyde SCHEMBL7038566 | 0.85 | ALDH1A1 (0.70) | ALDH1A1CYP2A6ALDH3A1ALDH1A3MAPK1 | |
| Benzaldehyde SCHEMBL28089327 | 0.85 | ALDH1A1 (0.70) | ALDH1A1CYP2A6ALDH3A1ALDH1A3MAPK1 | |
| Benzaldehyde SCHEMBL28807025 | 0.85 | ALDH1A1 (0.70) | ALDH1A1CYP2A6ALDH3A1ALDH1A3MAPK1 | |
| Benzaldehyde SCHEMBL9780149 | 0.85 | ALDH1A1 (0.70) | ALDH1A1CYP2A6ALDH3A1ALDH1A3MAPK1 | |
| Benzaldehyde SCHEMBL27780794 | 0.84 | ALDH1A1 (0.88) | ALDH1A1CYP2A6MAPK1TDP1TSHR | |
| Benzaldehyde SCHEMBL9236967 | 0.84 | — | — | |
| Benzaldehyde SCHEMBL22400699 | 0.84 | ALDH1A1 (1.00) | ALDH1A1CYP2A6MAPK1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104244932-B | Inhibitors of arginase and their therapeutic applications | 马尔斯公司 | 2017-02-22 | — | — | CN | disclosed |
| US-8865658-B2 | Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides | AMBRX, INC. (US) | 2014-10-21 | — | — | US | disclosed |
| US-20120315686-A1 | COMPOSITIONS CONTAINING, METHODS INVOLVING, AND USES OF NON-NATURAL AMINO ACIDS AND POLYPEPTIDES | AMBRX, INC. (US) | 2012-12-13 | — | — | US | disclosed |
| US-8183326-B2 | A living polymer endcapped with an azine compound; uniformly distributed reinforcing particulate fillers; tire treads with increased balance between rolling resistance and traction | BRIDGESTONE CORPORATION (JP) | 2012-05-22 | — | — | US | disclosed |
| EP-2044129-B1 | VULCANIZATE COMPRISING AZINE FUNCTIONALIZED POLYMER | BRIDGESTONE CORP (JP) | 2011-02-16 | — | — | EP | disclosed |
| US-20080027171-A1 | A living polymer endcapped with an azine compound; uniformly distributed reinforcing particulate fillers; tire treads with increased balance between rolling resistance and traction | BRIDGESTONE CORPORATION | 2008-01-31 | — | — | US | disclosed |
| US-4196026-A | LOW MOLECULAR WEIGHT | WALKER FRANKLIN E | 1980-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120315686-A1 | COMPOSITIONS CONTAINING, METHODS INVOLVING, AND USES OF NON-NATURAL AMINO ACIDS AND POLYPEPTIDES | PTMS, DNPEP, ANPEP | ALDH1A1 4035/4885CYP2A6 4452/4885ALDH3A1 3388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.